User profiles for L. Martinet

Ludovic Martinet

Cancer Research Center of Toulouse INSERM
Verified email at inserm.fr
Cited by 4799

Balancing natural killer cell activation through paired receptors

L Martinet, MJ Smyth - Nature Reviews Immunology, 2015 - nature.com
Natural killer (NK) cells are innate lymphocytes that are crucial for the control of infections
and malignancies. NK cells express a variety of inhibitory and activating receptors that …

[HTML][HTML] Molecular mechanisms of natural killer cell activation in response to cellular stress

CJ Chan, MJ Smyth, L Martinet - Cell Death & Differentiation, 2014 - nature.com
Protection against cellular stress from various sources, such as nutritional, physical, pathogenic,
or oncogenic, results in the induction of both intrinsic and extrinsic cellular protection …

DNAM‐1 control of natural killer cells functions through nectin and nectin‐like proteins

…, MJ Smyth, L Martinet - Immunology and cell …, 2014 - Wiley Online Library
Natural killer (NK) cells represent key innate immune cells that restrain viral infection and
malignant transformation and help mount an adaptive immune response. To perform such …

The receptors CD96 and CD226 oppose each other in the regulation of natural killer cell functions

CJ Chan, L Martinet, S Gilfillan… - Nature …, 2014 - nature.com
CD96, CD226 (DNAM-1) and TIGIT belong to an emerging family of receptors that interact
with nectin and nectin-like proteins. CD226 activates natural killer (NK) cell–mediated …

Human solid tumors contain high endothelial venules: association with T-and B-lymphocyte infiltration and favorable prognosis in breast cancer

L Martinet, I Garrido, T Filleron, S Le Guellec, E Bellard… - Cancer research, 2011 - AACR
The mechanisms governing infiltration of lymphocytes into tumors remain poorly characterized,
in spite of the critical impact of these cells on patient prognosis and therapeutic responses…

[HTML][HTML] Is dark matter in spiral galaxies cold gas? I. Observational constraints and dynamical clues about galaxy evolution

…, F Combes, L Martinet - … , Vol. 285, p. 79-93 (1994), 1994 - adsabs.harvard.edu
Based on dynamical constraints about the Hubble sequence evolution, observational data
and a number of" conspiracies", we propose that the dark matter around spiral galaxies is in …

[HTML][HTML] Disc galaxies with multiple triaxial structures. I. BVRI and Halpha surface photometry.

H Wozniak, D Friedli, L Martinet… - … Supplement, v. 111 …, 1995 - adsabs.harvard.edu
… bar for the bar with the larger spatial extent l~ and the … we have defined the luminosity L~
or L8 as being the luminosity inside the isophote of semi-major axis length l~ or l~ … value …

[HTML][HTML] Bars Within Bars in Lenticular and Spiral Galaxies-a Step in Secular Evolution

D Friedli, L Martinet - Astronomy and Astrophysics, Vol. 277, NO …, 1993 - adsabs.harvard.edu
Martinet: Bars within bars in lenticular and spiral galaxies … This paper, following a brief
first report (Friedli & Martinet 1993), is constructed as follows: Observations have been …

TIGIT immune checkpoint blockade restores CD8+ T-cell immunity against multiple myeloma

…, MWL Teng, K Nakamura, L Martinet… - Blood, The Journal …, 2018 - ashpublications.org
Immune-based therapies hold promise for the treatment of multiple myeloma (MM), but so far,
immune checkpoint blockade targeting programmed cell death protein 1 has not proven …

Suppression of metastases using a new lymphocyte checkpoint target for cancer immunotherapy

…, JJ Miles, VP Lutzky, LF de Andrade, L Martinet… - Cancer discovery, 2016 - AACR
CD96 has recently been shown as a negative regulator of mouse natural killer (NK)–cell
activity, with Cd96 −/− mice displaying hyperresponsive NK cells upon immune challenge. In …