We present an Aboriginal Australian genomic sequence obtained from a 100-year-old lock
of hair donated by an Aboriginal man from southern Western Australia in the early 20th …

Inference of population structure and individual ancestry is important both for population
genetics and for association studies. With next generation sequencing technologies it is …

The indigenous people of Greenland, the Inuit, have lived for a long time in the extreme
conditions of the Arctic, including low annual temperatures, and with a specialized diet rich in …

Background: Although the role of human papilloma virus (HPV) in cervical squamous cell
carcinoma (CSCC) is well established, the role in head and neck SCC (HNSCC) is less clear. …

Metabolism during pregnancy is a dynamic and precisely programmed process, the failure
of which can bring devastating consequences to the mother and fetus. To define a high-…

Preeclampsia is a serious complication of pregnancy, affecting both maternal and fetal health.
In genome-wide association meta-analysis of European and Central Asian mothers, we …

Noninvasive blood tests that provide information about fetal development and gestational
age could potentially improve prenatal care. Ultrasound, the current gold standard, is not …

Aims/hypothesis Human complex metabolic traits are in part regulated by genetic
determinants. Here we applied exome sequencing to identify novel associations of coding …

The timing of parturition is crucial for neonatal survival and infant health. Yet, its genetic
basis remains largely unresolved. We present a maternal genome-wide meta-analysis of …

A well-functioning placenta is essential for fetal and maternal health throughout pregnancy.
Using placental weight as a proxy for placental growth, we report genome-wide association …