A genome-wide survival analysis of 14,406 Alzheimer's disease (AD) cases and 25,849
controls identified eight previously reported AD risk loci and 14 novel loci associated with age at …

Soluble triggering receptor expressed on myeloid cells 2 (sTREM2) in cerebrospinal fluid (CSF)
has been associated with Alzheimer’s disease (AD). TREM2 plays a critical role in …

Understanding the tissue-specific genetic controls of protein levels is essential to uncover
mechanisms of post-transcriptional gene regulation. In this study, we generated a genomic …

Parietal cortex RNA-sequencing (RNA-seq) data were generated from individuals with and
without Alzheimer disease (AD; n control = 13; n AD = 83) from the Knight Alzheimer Disease …

Rationale: Ischemic stroke is among the leading causes of adult disability. Part of the variability
in functional outcome after stroke has been attributed to genetic factors but no locus has …

Background Alzheimer’s disease (AD) is the most common form of dementia. This
neurodegenerative disorder is associated with neuronal death and gliosis heavily impacting the …

Objective To determine whether the extent of overlap of the genetic architecture among the
sporadic late-onset Alzheimer's Disease (sLOAD), familial late-onset AD (fLOAD), sporadic …

Currently, neuropsychological impairment among HIV+ patients on antiretroviral therapy
leads to a reduction in the quality of life and it is an important challenge due to the high …

Antipsychotic drugs fail to achieve adequate response in 30–50% of treated patients and
about 50% of them develop severe and lasting side effects. Treatment failure results in poorer …

An effective visible-light-promoted iridium(III)-catalyzed hydrogen production from N-heterocycles
is described. A single iridium complex constitutes the photocatalytic system playing a …