User profiles for Louise V Wain
Louise V WainUniversity of Leicester Verified email at leicester.ac.uk Cited by 20905 |
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk
…, TH Mosley, S Seshadri, NRG Shrine, LV Wain… - Nature, 2011 - nature.com
Blood pressure is a heritable trait 1 influenced by several biological pathways and responsive
to environmental stimuli. Over one billion people worldwide have hypertension (≥140 mm …
to environmental stimuli. Over one billion people worldwide have hypertension (≥140 mm …
[HTML][HTML] Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study
Background The impact of COVID-19 on physical and mental health and employment after
hospitalisation with acute disease is not well understood. The aim of this study was to …
hospitalisation with acute disease is not well understood. The aim of this study was to …
Genome-wide association study identifies eight loci associated with blood pressure
…, DE Grobbee, NC Onland-Moret, ML Bots, LV Wain… - Nature …, 2009 - nature.com
Elevated blood pressure is a common, heritable cause of cardiovascular disease worldwide.
To date, identification of common genetic variants influencing blood pressure has proven …
To date, identification of common genetic variants influencing blood pressure has proven …
Chimpanzee reservoirs of pandemic and nonpandemic HIV-1
…, ML Santiago, F Bibollet-Ruche, Y Chen, LV Wain… - Science, 2006 - science.org
Human immunodeficiency virus type 1 (HIV-1), the cause of human acquired immunodeficiency
syndrome (AIDS), is a zoonotic infection of staggering proportions and social impact. Yet …
syndrome (AIDS), is a zoonotic infection of staggering proportions and social impact. Yet …
Genome-wide association study identifies five loci associated with lung function
Pulmonary function measures are heritable traits that predict morbidity and mortality and
define chronic obstructive pulmonary disease (COPD). We tested genome-wide association …
define chronic obstructive pulmonary disease (COPD). We tested genome-wide association …
Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk
Elevated blood pressure is the leading heritable risk factor for cardiovascular disease
worldwide. We report genetic association of blood pressure (systolic, diastolic, pulse pressure) …
worldwide. We report genetic association of blood pressure (systolic, diastolic, pulse pressure) …
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure
Numerous genetic loci have been associated with systolic blood pressure (SBP) and diastolic
blood pressure (DBP) in Europeans 1, 2, 3. We now report genome-wide association …
blood pressure (DBP) in Europeans 1, 2, 3. We now report genome-wide association …
Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes
Although several lung cancer susceptibility loci have been identified, much of the heritability
for lung cancer remains unexplained. Here 14,803 cases and 12,262 controls of European …
for lung cancer remains unexplained. Here 14,803 cases and 12,262 controls of European …
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function
Pulmonary function measures reflect respiratory health and are used in the diagnosis of
chronic obstructive pulmonary disease. We tested genome-wide association with forced …
chronic obstructive pulmonary disease. We tested genome-wide association with forced …
[HTML][HTML] Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in …
Background Understanding the genetic basis of airflow obstruction and smoking behaviour
is key to determining the pathophysiology of chronic obstructive pulmonary disease (COPD). …
is key to determining the pathophysiology of chronic obstructive pulmonary disease (COPD). …