The lion's share of bacteria in various environments cannot be cloned in the laboratory and
thus cannot be sequenced using existing technologies. A major goal of single-cell genomics …

Recent advances in single-cell genomics provide an alternative to largely gene-centric
metagenomics studies, enabling whole-genome sequencing of uncultivated bacteria. However, …

INTRODUCTION Control of mosquito vectors has historically proven to be an effective
means of eliminating malaria. Human malaria is transmitted only by mosquitoes in the genus …

Recent advances in single-cell genomics provide an alternative to gene-centric metagenomics
studies, enabling whole genome sequencing of uncultivated bacteria. However, single-…

Error correction of sequenced reads remains a difficult task, especially in single-cell
sequencing projects with extremely non-uniform coverage. While existing error correction tools …

Recently completed whole-genome sequencing projects marked the transition from gene-based
phylogenetic studies to phylogenomics analysis of entire genomes. We developed an …

Since most dramatic genomic changes are caused by genome rearrangements as well as
gene duplications and gain/loss events, it becomes crucial to understand their mechanisms …

… In particular, Alekseyev and Pevzner [24] succeeded in solving the 3-Break Genome
Halving problem while there is currently no solution known to the similar problem involving …

Background New sequencing technologies have lowered financial barriers to whole
genome sequencing, but resulting assemblies are often fragmented and far from ‘finished’. …

… Alekseyev received the MS degree in mathematics from Nizhni Novgorod State University
in 1999. He is pursuing the PhD degree in computer science at University of California San …