User profiles for M. E. McCue
Molly McCueUniversity Of Minnesota Verified email at umn.edu Cited by 5503 |
[HTML][HTML] A vision for development and utilization of high-throughput phenotyping and big data analytics in livestock
Automated high-throughput phenotyping with sensors, imaging, and other on-farm technologies
has resulted in a flood of data that are largely under-utilized. Drastic cost reductions in …
has resulted in a flood of data that are largely under-utilized. Drastic cost reductions in …
Equine metabolic syndrome: a complex disease influenced by genetics and the environment
Equine metabolic syndrome (EMS) refers to a cluster of clinical abnormalities including
insulin resistance, generalized obesity, and/or increased adiposity in specific locations (regional …
insulin resistance, generalized obesity, and/or increased adiposity in specific locations (regional …
[HTML][HTML] The scope of big data in one medicine: unprecedented opportunities and challenges
Advances in high-throughput molecular biology and electronic health records (EHR), coupled
with increasing computer capabilities have resulted in an increased interest in the use of …
with increasing computer capabilities have resulted in an increased interest in the use of …
[HTML][HTML] Mutations in DMRT3 affect locomotion in horses and spinal circuit function in mice
…, G Hjälm, F Imsland, JL Petersen, ME McCue… - Nature, 2012 - nature.com
Locomotion in mammals relies on a central pattern-generating circuitry of spinal interneurons
established during development that coordinates limb movement 1 . These networks …
established during development that coordinates limb movement 1 . These networks …
[HTML][HTML] Genetic diversity in the modern horse illustrated from genome-wide SNP data
Horses were domesticated from the Eurasian steppes 5,000–6,000 years ago. Since then,
the use of horses for transportation, warfare, and agriculture, as well as selection for desired …
the use of horses for transportation, warfare, and agriculture, as well as selection for desired …
[HTML][HTML] Genome-wide analysis reveals selection for important traits in domestic horse breeds
Intense selective pressures applied over short evolutionary time have resulted in homogeneity
within, but substantial variation among, horse breeds. Utilizing this population structure, …
within, but substantial variation among, horse breeds. Utilizing this population structure, …
[HTML][HTML] A high density SNP array for the domestic horse and extant Perissodactyla: utility for association mapping, genetic diversity, and phylogeny studies
An equine SNP genotyping array was developed and evaluated on a panel of samples
representing 14 domestic horse breeds and 18 evolutionarily related species. More than 54,000 …
representing 14 domestic horse breeds and 18 evolutionarily related species. More than 54,000 …
[HTML][HTML] Glycogen synthase (GYS1) mutation causes a novel skeletal muscle glycogenosis
Polysaccharide storage myopathy (PSSM) is a novel glycogenosis in horses characterized
by abnormal glycogen accumulation in skeletal muscle and muscle damage with exertion. It …
by abnormal glycogen accumulation in skeletal muscle and muscle damage with exertion. It …
[HTML][HTML] Improved reference genome for the domestic horse increases assembly contiguity and composition
Recent advances in genomic sequencing technology and computational assembly methods
have allowed scientists to improve reference genome assemblies in terms of contiguity and …
have allowed scientists to improve reference genome assemblies in terms of contiguity and …
[HTML][HTML] Developing a 670k genotyping array to tag~ 2M SNPs across 24 horse breeds
Background To date, genome-scale analyses in the domestic horse have been limited by
suboptimal single nucleotide polymorphism (SNP) density and uneven genomic coverage of …
suboptimal single nucleotide polymorphism (SNP) density and uneven genomic coverage of …