User profiles for M. E. McCue

Molly McCue

University Of Minnesota
Verified email at umn.edu
Cited by 5503

[HTML][HTML] A vision for development and utilization of high-throughput phenotyping and big data analytics in livestock

…, RN Dilger, LM Kramer, JK Lunney, ME McCue… - Frontiers in …, 2019 - frontiersin.org
Automated high-throughput phenotyping with sensors, imaging, and other on-farm technologies
has resulted in a flood of data that are largely under-utilized. Drastic cost reductions in …

Equine metabolic syndrome: a complex disease influenced by genetics and the environment

ME McCue, RJ Geor, N Schultz - Journal of Equine Veterinary Science, 2015 - Elsevier
Equine metabolic syndrome (EMS) refers to a cluster of clinical abnormalities including
insulin resistance, generalized obesity, and/or increased adiposity in specific locations (regional …

[HTML][HTML] The scope of big data in one medicine: unprecedented opportunities and challenges

ME McCue, AM McCoy - Frontiers in veterinary science, 2017 - frontiersin.org
Advances in high-throughput molecular biology and electronic health records (EHR), coupled
with increasing computer capabilities have resulted in an increased interest in the use of …

[HTML][HTML] Mutations in DMRT3 affect locomotion in horses and spinal circuit function in mice

…, G Hjälm, F Imsland, JL Petersen, ME McCue… - Nature, 2012 - nature.com
Locomotion in mammals relies on a central pattern-generating circuitry of spinal interneurons
established during development that coordinates limb movement 1 . These networks …

[HTML][HTML] Genetic diversity in the modern horse illustrated from genome-wide SNP data

…, T Tozaki, M Vaudin, C M. Wade, ME McCue - PloS one, 2013 - journals.plos.org
Horses were domesticated from the Eurasian steppes 5,000–6,000 years ago. Since then,
the use of horses for transportation, warfare, and agriculture, as well as selection for desired …

[HTML][HTML] Genome-wide analysis reveals selection for important traits in domestic horse breeds

…, T Tozaki, M Vaudin, CM Wade, ME McCue - PLoS …, 2013 - journals.plos.org
Intense selective pressures applied over short evolutionary time have resulted in homogeneity
within, but substantial variation among, horse breeds. Utilizing this population structure, …

[HTML][HTML] A high density SNP array for the domestic horse and extant Perissodactyla: utility for association mapping, genetic diversity, and phylogeny studies

ME McCue, DL Bannasch, JL Petersen, J Gurr… - PLoS …, 2012 - journals.plos.org
An equine SNP genotyping array was developed and evaluated on a panel of samples
representing 14 domestic horse breeds and 18 evolutionarily related species. More than 54,000 …

[HTML][HTML] Glycogen synthase (GYS1) mutation causes a novel skeletal muscle glycogenosis

ME McCue, SJ Valberg, MB Miller, C Wade, S DiMauro… - Genomics, 2008 - Elsevier
Polysaccharide storage myopathy (PSSM) is a novel glycogenosis in horses characterized
by abnormal glycogen accumulation in skeletal muscle and muscle damage with exertion. It …

[HTML][HTML] Improved reference genome for the domestic horse increases assembly contiguity and composition

…, CJ Finno, RR Bellone, ME McCue… - Communications …, 2018 - nature.com
Recent advances in genomic sequencing technology and computational assembly methods
have allowed scientists to improve reference genome assemblies in terms of contiguity and …

[HTML][HTML] Developing a 670k genotyping array to tag~ 2M SNPs across 24 horse breeds

…, B Wallner, L Orlando, JR Mickelson, ME McCue - BMC genomics, 2017 - Springer
Background To date, genome-scale analyses in the domestic horse have been limited by
suboptimal single nucleotide polymorphism (SNP) density and uneven genomic coverage of …