User profiles for M. L. Szpara
Moriah L. SzparaPennsylvania State University Verified email at psu.edu Cited by 2335 |
ICTV Virus Taxonomy Profile: Herpesviridae 2021
…, CA Hartley, ML Szpara… - Journal of General …, 2021 - microbiologyresearch.org
Members of the family Herpesviridae have enveloped, spherical virions with characteristic
complex structures consisting of symmetrical and non-symmetrical components. The linear, …
complex structures consisting of symmetrical and non-symmetrical components. The linear, …
Impacts of genome-wide analyses on our understanding of human herpesvirus diversity and evolution
… We thank our reviewers, members of the Szpara laboratory, and our many colleagues for …
Renner also helped to produce and continues to support the Szpara laboratory's public open-…
Renner also helped to produce and continues to support the Szpara laboratory's public open-…
Differentiation of the SH-SY5Y human neuroblastoma cell line
… To heat-inactivate, warm a 50 ml aliquot of FBS at 56 C for 30 min, inverting every 10 min
(… For example, 50 ml of media takes approximately one hour to fully equilibrate (pH 7, 37 C, 5…
(… For example, 50 ml of media takes approximately one hour to fully equilibrate (pH 7, 37 C, 5…
Evolution and diversity in human herpes simplex virus genomes
Herpes simplex virus 1 (HSV-1) causes a chronic, lifelong infection in >60% of adults. Multiple
recent vaccine trials have failed, with viral diversity likely contributing to these failures. To …
recent vaccine trials have failed, with viral diversity likely contributing to these failures. To …
[HTML][HTML] Interferon-independent STING signaling promotes resistance to HSV-1 in vivo
… cells at a final concentration of 4 μg/ml (six-well plates). For SeV, cells were infected at 150
hemagglutination units (HAU)/ml. For poly I:C, 2 mg/ml of the stock solution was heated at 50 …
hemagglutination units (HAU)/ml. For poly I:C, 2 mg/ml of the stock solution was heated at 50 …
[HTML][HTML] Persistent infection with herpes simplex virus 1 and Alzheimer's disease—a call to study how variability in both virus and host may impact disease
CA Mangold, ML Szpara - Viruses, 2019 - mdpi.com
Increasing attention has focused on the contributions of persistent microbial infections with
the manifestation of disease later in life, including neurodegenerative conditions such as …
the manifestation of disease later in life, including neurodegenerative conditions such as …
Sequence variability in clinical and laboratory isolates of herpes simplex virus 1 reveals new mutations
Herpes simplex virus 1 (HSV-1) is a well-adapted human pathogen that can invade the
peripheral nervous system and persist there as a lifelong latent infection. Despite their ubiquity, …
peripheral nervous system and persist there as a lifelong latent infection. Despite their ubiquity, …
[HTML][HTML] A wide extent of inter-strain diversity in virulent and vaccine strains of alphaherpesviruses
Alphaherpesviruses are widespread in the human population, and include herpes simplex
virus 1 (HSV-1) and 2, and varicella zoster virus (VZV). These viral pathogens cause …
virus 1 (HSV-1) and 2, and varicella zoster virus (VZV). These viral pathogens cause …
A phylogenomic analysis of Marek's disease virus reveals independent paths to virulence in Eurasia and North America
… alignment after inspection of a linear regression between ML tree root-to-tip divergences and
… The impact of the recombinant regions on ML tree topology was minimal, but their removal …
… The impact of the recombinant regions on ML tree topology was minimal, but their removal …
[HTML][HTML] Dermatitis during spaceflight associated with HSV-1 reactivation
SK Mehta, ML Szpara, BV Rooney, DM Diak… - Viruses, 2022 - mdpi.com
… A single peripheral blood sample using an 8.5 mL heparin anti-coagulated tube and a 24
h urine pool were also collected, each mission time point (Figure 1). Only one blood sample …
h urine pool were also collected, each mission time point (Figure 1). Only one blood sample …