Post-mortem tissues samples are a key resource for investigating patterns of gene expression.
However, the processes triggered by death and the post-mortem interval (PMI) can …

Understanding the aspects of cell functionality that account for disease mechanisms or drug
modes of action is a main challenge for precision medicine. Classical gene-based …

Simple Summary Differences in epidemiological and clinical patterns of lung adenocarcinoma
have been described between male and female patients. Our study aimed to assess the …

Simple Summary Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal disease with
a few curative options. Desmoplastic stroma and immune system evasion in PDAC represent …

Babelomics has been running for more than one decade offering a user-friendly interface
for the functional analysis of gene expression and genomic data. Here we present its fifth …

Understanding the aspects of the cell functionality that account for disease or drug action
mechanisms is a main challenge for precision medicine. Here we propose a new method that …

In recent decades, increasing longevity (among other factors) has fostered a rise in Parkinson's
disease incidence. Although not exhaustively studied in this devastating disease, the …

Metabolic reprogramming plays an important role in cancer development and progression
and is a well-established hallmark of cancer. Despite its inherent complexity, cellular …

Background Multiple sclerosis (MS), a chronic auto-immune, inflammatory, and degenerative
disease of the central nervous system, affects both males and females; however, females …

In spite of the increasing availability of genomic and transcriptomic data, there is still a gap
between the detection of perturbations in gene expression and the understanding of their …