User profiles for M. S. Gelfand

Mikhail Gelfand

Vice-President for Biomedical Research, Skoltech
Verified email at skoltech.ru
Cited by 20849

Riboswitches: the oldest mechanism for the regulation of gene expression?

…, DA Rodionov, AA Mironov, MS Gelfand - TRENDS in Genetics, 2004 - cell.com
Riboswitches are structures that form in mRNA and regulate gene expression in bacteria.
Unlike other known RNA regulatory structures, they are directly bound by small ligands. The …

A conserved RNA structure element involved in the regulation of bacterial riboflavin synthesis genes

MS Gelfand, AA Mironov, J Jomantas, YI Kozlov… - Trends in Genetics, 1999 - cell.com
An alternative possibility is that recombination, proportional GC content and intron size do
show covariance, but not in the same way in all vertebrates. It might be that in chickens and …

Increase of functional diversity by alternative splicing

…, I Koch, R Apweiler, M Vingron, P Bork, MS Gelfand… - Trends in Genetics, 2003 - cell.com
A large-scale analysis of protein isoforms arising from alternative splicing shows that
alternative splicing tends to insert or delete complete protein domains more frequently than …

Experimental Determination and System Level Analysis of Essential Genes in Escherichia coli MG1655

…, NC Kyrpides, I Anderson, MS Gelfand… - Journal of …, 2003 - Am Soc Microbiol
Defining the gene products that play an essential role in an organism's functional repertoire
is vital to understanding the system level organization of living cells. We used a genetic …

Frequent alternative splicing of human genes

AA Mironov, JW Fickett, MS Gelfand - Genome research, 1999 - genome.cshlp.org
Alternative splicing can produce variant proteins and expression patterns as different as the
products of different genes, yet the prevalence of alternative splicing has not been quantified…

[HTML][HTML] Comparative genomics of the vitamin B12 metabolism and regulation in prokaryotes

…, AG Vitreschak, AA Mironov, MS Gelfand - Journal of Biological …, 2003 - ASBMB
Using comparative analysis of genes, operons, and regulatory elements, we describe the
cobalamin (vitamin B 12 ) biosynthetic pathway in available prokaryotic genomes. Here we …

[HTML][HTML] Comparative genomics of thiamin biosynthesis in procaryotes: new genes and regulatory mechanisms

…, AG Vitreschak, AA Mironov, MS Gelfand - Journal of Biological …, 2002 - ASBMB
Vitamin B 1 in its active form thiamin pyrophosphate is an essential coenzyme that is
synthesized by coupling of pyrimidine (hydroxymethylpyrimidine; HMP) and thiazole (…

Regulation of riboflavin biosynthesis and transport genes in bacteria by transcriptional and translational attenuation

…, DA Rodionov, AA Mironov, MS Gelfand - Nucleic acids …, 2002 - academic.oup.com
The riboflavin biosynthesis in bacteria was analyzed using comparative analysis of genes,
operons and regulatory elements. A model for regulation based on formation of alternative …

Enterobacter sakazakii infections in neonates associated with intrinsic contamination of a powdered infant formula

BP Simmons, MS Gelfand, M Haas, L Metts… - Infection Control & …, 1989 - cambridge.org
We report an outbreak of Enterobacter sakazakii infection and colonization in neonates
related to an infant formula contaminated during the manufacturing process. The outbreak …

Active chromatin and transcription play a key role in chromosome partitioning into topologically associating domains

…, MV Imakaev, A Chertovich, MS Gelfand… - Genome …, 2016 - genome.cshlp.org
… To ensure that we did not miss any TAD boundaries enriched with dCTCF or Su(Hw), we
repeated the TAD calling procedure for values of γ ranging from 0 to 3.2 with a step of 0.2. We …