Remarkable advances in DNA sequencing technology have created a need for de novo
genome assembly methods tailored to work with the new sequencing data types. Many such …

Next-generation DNA sequencing coupled with chromatin immunoprecipitation (ChIP-seq)
is revolutionizing our ability to interrogate whole genome protein-DNA interactions. …

We report the complete sequence of the 4,274,642-bp genome of Haloarcula marismortui, a
halophilic archaeal isolate from the Dead Sea. The genome is organized into nine circular …

The environment significantly influences the dynamic expression and assembly of all
components encoded in the genome of an organism into functional biological networks. We have …

Organisms across the tree of life use a variety of mechanisms to respond to stress-inducing
fluctuations in osmotic conditions. Cellular response mechanisms and phenotypes …

High-throughput DNA sequencing technologies have spurred the development of numerous
novel methods for genome assembly. With few exceptions, these algorithms are heuristic …

Despite the knowledge of complex prokaryotic‐transcription mechanisms, generalized rules,
such as the simplified organization of genes into operons with well‐defined promoters and …

Rationale: A high-fat diet accompanied by hypertriglyceridemia increases an individual’s risk
for development of atherosclerosis. An early event in this process is monocyte recruitment …

Frankia strains are nitrogen-fixing soil actinobacteria that can form root symbioses with
actinorhizal plants. Phylogenetically, symbiotic frankiae can be divided into three clusters, and …

… on the basis of mRNA level changes and putative functions, the regulatory control imposed
by the GTFs were experimentally measured with ChIP-chip (MT Facciotti, M. Pan, A. Kaur, M. …