Despite improvements in genomics technology, the detection of structural variants (SVs) from
short-read sequencing still poses challenges, particularly for complex variation. Here we …

Birdshot Uveitis (Birdshot) is a rare eye condition that affects HLA-A29-positive individuals
and could be considered a prototypic member of the recently proposed ‘MHC-I (major …

HLA-G expressed by trophoblasts at the fetal-maternal interface and its soluble form have
immunomodulatory effects. HLA-G expression depends on the combination of DNA …

Germline mutation detection from human DNA sequence data is challenging due to the
rarity of such events relative to the intrinsic error rates of sequencing technologies and the …

We address the problem of accurately and efficiently identifying de-novo mutations in the
human germline. More precisely, how can we detect de-novo point mutations on the sex …

A long-standing hypothesis in biology proposes that various species select mates with a major
histocompatibility complex (MHC) composition divergent from their own, so as to improve …

Astrojunior project was a success, as most participants are already looking forward for the
next programme. The on-line workshops are beeing implemented for a long-term schedule, as …