Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa
Characterized primarily by a low body-mass index, anorexia nervosa is a complex and
serious illness 1 , affecting 0.9–4% of women and 0.3% of men 2 , 3 – 4 , with twin-based …
serious illness 1 , affecting 0.9–4% of women and 0.3% of men 2 , 3 – 4 , with twin-based …
A genome-wide association study of anorexia nervosa
…, M Gratacos, F Rybakowski, M Dmitrzak-Weglarz… - Molecular …, 2014 - nature.com
Anorexia nervosa (AN) is a complex and heritable eating disorder characterized by
dangerously low body weight. Neither candidate gene studies nor an initial genome-wide …
dangerously low body weight. Neither candidate gene studies nor an initial genome-wide …
Pathophysiology of depression: Molecular regulation of melatonin homeostasis–current status
M Dmitrzak-Weglarz, E Reszka - Neuropsychobiology, 2018 - karger.com
Circadian rhythm alterations resulting in disturbed sleep and disturbed melatonin secretion
are flagship features of depression. Melatonin, known as a hormone of darkness, is secreted …
are flagship features of depression. Melatonin, known as a hormone of darkness, is secreted …
Differential efficacy of escitalopram and nortriptyline on dimensional measures of depression
…, M Rietschel, A Zobel, M Dmitrzak-Weglarz… - The British Journal of …, 2009 - cambridge.org
BackgroundTricyclic antidepressants and serotonin reuptake inhibitors are considered to be
equally effective, but differences may have been obscured by internally inconsistent …
equally effective, but differences may have been obscured by internally inconsistent …
[HTML][HTML] Biomarkers in child and adolescent depression
W Zwolińska, M Dmitrzak-Węglarz… - Child Psychiatry & Human …, 2023 - Springer
Despite the significant prevalence of Major Depressive Disorder in the pediatric population,
the pathophysiology of this condition remains unclear, and the treatment outcomes poor. …
the pathophysiology of this condition remains unclear, and the treatment outcomes poor. …
[HTML][HTML] Neurobiochemical and psychological factors influencing the eating behaviors and attitudes in anorexia nervosa
…, E Paszynska, M Dmitrzak-Weglarz… - Journal of physiology …, 2017 - Springer
The aim of this study was to determine the characteristic features which contribute to
inappropriate eating attitudes in people suffering from anorexia nervosa, based on an analysis of …
inappropriate eating attitudes in people suffering from anorexia nervosa, based on an analysis of …
Glucocorticoid receptor polymorphism is associated with major depression and predominance of depression in the course of bipolar disorder
…, M Dmitrzak-Weglarz, M Wilkosc, M Skibinska… - Journal of Affective …, 2011 - Elsevier
BACKGROUND: A strong association has been found between dysregulation of
hypothalamic–pituitary–adrenal (HPA) axis and depression and bipolar disorder. Glucocorticoid …
hypothalamic–pituitary–adrenal (HPA) axis and depression and bipolar disorder. Glucocorticoid …
Interaction between serotonin transporter gene variants and life events predicts response to antidepressants in the GENDEP project
…, ER Larsen, M Dmitrzak-Weglarz… - The …, 2011 - nature.com
There is substantial inter-individual variation in response to antidepressants, and genetic
variation may, in part, explain these differences. For example, there is evidence to suggest that …
variation may, in part, explain these differences. For example, there is evidence to suggest that …
Shared genetic risk between eating disorder‐and substance‐use‐related phenotypes: Evidence from genome‐wide association studies
Eating disorders and substance use disorders frequently co‐occur. Twin studies reveal
shared genetic variance between liabilities to eating disorders and substance use, with the …
shared genetic variance between liabilities to eating disorders and substance use, with the …
Polymorphism of circadian clock genes and prophylactic lithium response
JK Rybakowski, M Dmitrzak‐Weglarz… - Bipolar …, 2014 - Wiley Online Library
Objectives The therapeutic action of lithium in bipolar mood disorder may be connected with
its effect on biological rhythms. In the present study, an attempt was made to investigate an …
its effect on biological rhythms. In the present study, an attempt was made to investigate an …