User profiles for M. Doumith
Michel DoumithScientist - Bioinformatician Verified email at ukhsa.gov.uk Cited by 15536 |
[HTML][HTML] The role of whole genome sequencing in antimicrobial susceptibility testing of bacteria: report from the EUCAST Subcommittee
Whole genome sequencing (WGS) offers the potential to predict antimicrobial susceptibility
from a single assay. The European Committee on Antimicrobial Susceptibility Testing …
from a single assay. The European Committee on Antimicrobial Susceptibility Testing …
[HTML][HTML] Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study
…, R Balakrishnan, U Chaudhary, M Doumith… - The Lancet infectious …, 2010 - thelancet.com
Background Gram-negative Enterobacteriaceae with resistance to carbapenem conferred
by New Delhi metallo-β-lactamase 1 (NDM-1) are potentially a major global health problem. …
by New Delhi metallo-β-lactamase 1 (NDM-1) are potentially a major global health problem. …
Differentiation of the Major Listeria monocytogenes Serovars by Multiplex PCR
A new multiplex PCR assay was developed to separate the four major Listeria monocytogenes
serovars isolated from food and patients (1/2a, 1/2b, 1/2c, and 4b) into distinct groups. …
serovars isolated from food and patients (1/2a, 1/2b, 1/2c, and 4b) into distinct groups. …
Pathogenomics of Listeria spp.
This review provides an overview of recent progress in the exploration of genomic, transcriptomic,
and proteomic data in Listeria spp. to understand genome evolution and diversity, as …
and proteomic data in Listeria spp. to understand genome evolution and diversity, as …
Molecular mechanisms disrupting porin expression in ertapenem-resistant Klebsiella and Enterobacter spp. clinical isolates from the UK
M Doumith, MJ Ellington, DM Livermore… - Journal of …, 2009 - academic.oup.com
Objectives The aim of this study was to investigate relatedness and molecular mechanism(s)
of ertapenem resistance in clinical isolates of Klebsiella spp. (n = 28) and Enterobacter spp. …
of ertapenem resistance in clinical isolates of Klebsiella spp. (n = 28) and Enterobacter spp. …
Phosphoethanolamine modification of lipid A in colistin-resistant variants of Acinetobacter baumannii mediated by the pmrAB two-component regulatory system
Colistin resistance is rare in Acinetobacter baumannii , and little is known about its mechanism.
We investigated the role of PmrCAB in this trait, using (i) resistant and susceptible clinical …
We investigated the role of PmrCAB in this trait, using (i) resistant and susceptible clinical …
What remains against carbapenem-resistant Enterobacteriaceae? Evaluation of chloramphenicol, ciprofloxacin, colistin, fosfomycin, minocycline, nitrofurantoin …
…, M Warner, S Mushtaq, M Doumith… - International journal of …, 2011 - Elsevier
Carbapenem-resistant Enterobacteriaceae present an increasing and diverse problem,
including strains of multiple species with metallo-β-lactamases (IMP, NDM or VIM) and non-…
including strains of multiple species with metallo-β-lactamases (IMP, NDM or VIM) and non-…
Identification of bacterial pathogens and antimicrobial resistance directly from clinical urines by nanopore-based metagenomic sequencing
…, LC Crossman, M Doumith… - Journal of …, 2016 - academic.oup.com
Objectives The introduction of metagenomic sequencing to diagnostic microbiology has
been hampered by slowness, cost and complexity. We explored whether MinION nanopore …
been hampered by slowness, cost and complexity. We explored whether MinION nanopore …
[HTML][HTML] Methicillin-resistant Staphylococcus aureus emerged long before the introduction of methicillin into clinical practice
Background The spread of drug-resistant bacterial pathogens poses a major threat to global
health. It is widely recognised that the widespread use of antibiotics has generated selective …
health. It is widely recognised that the widespread use of antibiotics has generated selective …
New Aspects Regarding Evolution and Virulence of Listeria monocytogenes Revealed by Comparative Genomics and DNA Arrays
M Doumith, C Cazalet, N Simoes, L Frangeul… - Infection and …, 2004 - Am Soc Microbiol
… array, combined with the knowledge of the marker genes identified in this study, should
prove to be a powerful tool for identifying these strains (M. Doumith, C. Buchrieser, P. Glaser, C. …
prove to be a powerful tool for identifying these strains (M. Doumith, C. Buchrieser, P. Glaser, C. …