User profiles for M. Heilemann

Mike Heilemann

Professor of Physical Chemistry, Goethe-University Frankfurt/M., Germany
Verified email at chemie.uni-frankfurt.de
Cited by 17457

Single-molecule localization microscopy in eukaryotes

M Sauer, M Heilemann - Chemical reviews, 2017 - ACS Publications
Super-resolution fluorescence imaging by photoactivation or photoswitching of single
fluorophores and position determination (single-molecule localization microscopy, SMLM) …

Live-cell super-resolution imaging with synthetic fluorophores

…, M Heilemann, M Sauer - Annual review of physical …, 2012 - annualreviews.org
Super-resolution imaging methods now can provide spatial resolution that is well below the
diffraction limit approaching virtually molecular resolution. They can be applied to biological …

[HTML][HTML] Subdiffraction-resolution fluorescence imaging with conventional fluorescent probes

M Heilemann, S Van De Linde… - Angewandte Chemie …, 2008 - pub.uni-bielefeld.de
Heilemann M, van de Linde S, Schüttpelz M, et al. Subdiffraction-resolution fluorescence
imaging with conventional fluorescent probes. ANGEWANDTE CHEMIE-INTERNATIONAL …

Multi‐colour direct STORM with red emitting carbocyanines

A Lampe, V Haucke, SJ Sigrist, M Heilemann… - Biology of the …, 2012 - Wiley Online Library
Background information Single molecule‐based super‐resolution methods have become
important tools to study nanoscale structures in cell biology. However, the complexity of multi‐…

Direct stochastic optical reconstruction microscopy with standard fluorescent probes

…, M Heidbreder, S Wolter, M Heilemann, M Sauer - Nature protocols, 2011 - nature.com
Direct stochastic optical reconstruction microscopy (dSTORM) uses conventional
fluorescent probes such as labeled antibodies or chemical tags for subdiffraction resolution …

[HTML][HTML] Democratising deep learning for microscopy with ZeroCostDL4Mic

…, C Leterrier, Y Shechtman, F Jug, M Heilemann… - Nature …, 2021 - nature.com
Deep Learning (DL) methods are powerful analytical tools for microscopy and can outperform
conventional image processing pipelines. Despite the enthusiasm and innovations fuelled …

[HTML][HTML] A reducing and oxidizing system minimizes photobleaching and blinking of fluorescent dyes

…, B Person, M Heilemann, M Sauer… - Angewandte Chemie …, 2008 - pub.uni-bielefeld.de
… van de Linde S, Heilemann M, Sauer M., Annu Rev Phys Chem 63(), 2012 … van de
Linde S, Löschberger A, Klein T, Heidbreder M, Wolter S, Heilemann M, Sauer M., Nat …

Carbocyanine dyes as efficient reversible single-molecule optical switch

M Heilemann, E Margeat, R Kasper… - Journal of the …, 2005 - ACS Publications
We demonstrate that commercially available unmodified carbocyanine dyes such as Cy5 (usually
excited at 633 nm) can be used as efficient reversible single-molecule optical switch, …

[HTML][HTML] Super-resolution imaging with small organic fluorophores

M Heilemann, S Van De Linde… - Angewandte Chemie …, 2009 - pub.uni-bielefeld.de
Heilemann M, van de Linde S, Mukherjee A, Sauer M. Super-Resolution Imaging with
Small Organic Fluorophores. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION …

Reconfigurable, braced, three-dimensional DNA nanostructures

RP Goodman, M Heilemann, S Doose… - Nature …, 2008 - nature.com
DNA nanotechnology makes use of the exquisite self-recognition of DNA in order to build on
a molecular scale 1 . Although static structures may find applications in structural biology 2 , …