Blood platelets are here presented as active players in antimicrobial host defense and the
induction of inflammation and tissue repair in addition to their participation in hemostasis. …

… are protein kinase A (PKA) and members of the nonreceptor tyrosine kinase family Src
because A 2A -dependent ERK activation can be blocked by appropriate inhibitors (Klinger M, …

Besides their functions in the haemostatic process and in thrombus formation after an endothelial
injury, blood platelets also take part in the processes of inflammation and tissue repair …

Post-acute sequelae of COVID-19 (PASC) represent an emerging global crisis. However,
quantifiable risk factors for PASC and their biological associations are poorly resolved. We …

… All seven patients treated at the recently completed dose level of 0.06 mg/m 2 showed … of
0.03 and 0.06 mg/m 2 per day. Blinatumomab doses of 0.015 mg/m 2 per day and higher led to …

Purpose Blinatumomab, a bispecific single-chain antibody targeting the CD19 antigen, is a
member of a novel class of antibodies that redirect T cells for selective lysis of tumor cells. In …

Persistence or recurrence of minimal residual disease (MRD) after chemotherapy results in
clinical relapse in patients with acute lymphoblastic leukemia (ALL). In a phase 2 trial of B-…

… In this trial, blinatumomab was continuously infused to patients by a portable mini-pump
and port system at a dose level of 15 μg/m 2 /d for 4 weeks. Subsequent treatment cycles were …

Background Despite civilization and progress, burns occur frequently in the world. Remarkable
discoveries of wound healing mechanisms have been reported. On the other hand, long-…

… MF were generated by culturing autologous monocytes for 2 days in complete RPMI 1640
medium supplemented with 10 ng/ml M-CSF (Peprotech). MF were coincubated with infected …