… Cela, HL Szabo-Rogers, contributed to data interpretation, drafted the manuscript; M. Kunova
Bosakova, contributed to data acquisition, analysis, and interpretation, critically revised the …

Fibroblast growth factors (FGFs) serve numerous regulatory functions in complex organisms,
and their corresponding therapeutic potential is of growing interest to academics and …

The short rib polydactyly syndromes (SRPS) are a group of recessively inherited, perinatal-lethal
skeletal disorders primarily characterized by short ribs, shortened long bones, varying …

Cilia project from almost every cell integrating extracellular cues with signaling pathways.
Constitutive activation of FGFR3 signaling produces the skeletal disorders achondroplasia (…

Vertebrate primary cilium is a Hedgehog signaling center but the extent of its involvement in
other signaling systems is less well understood. This report delineates a mechanism by …

Yersiniosis belongs to the common foodborne diseases around the world, and frequently
manifests as diarrhea that can be treated with probiotics. Colicin F Y is an antibacterial agent …

HMGB1 and HMGB2 proteins have been implicated in numerous cellular processes, including
proliferation, differentiation, apoptosis, and tumor growth. It is unknown whether they are …

… in 2% SDS, twice for 5 min at room temperature in 6 M Urea in PBS, and six times for 5 min
at room temperature in 1 M NaCl, 25% Acetonitrile and twice for 5 min at room temperature in …

Human embryonic stem cells (hESCs) represent a promising tool to study functions of genes
during development, to model diseases, and to even develop therapies when combined …

Objective Statins are widely used drugs for cholesterol lowering, which were recently found
to counteract the effects of aberrant fibroblast growth factor receptor (FGFR3) signaling in cell …