Fatty acid synthase as a potential therapeutic target in cancer
… for Translational Research, a gift from Nuclea Biomarkers to the Jimmy Fund and the Loda
laboratory. Massimo Loda is the recipient of a grant from the Dana Farber Cancer Institute–…
laboratory. Massimo Loda is the recipient of a grant from the Dana Farber Cancer Institute–…
[HTML][HTML] Lipids and cancer: Emerging roles in pathogenesis, diagnosis and therapeutic intervention
With the advent of effective tools to study lipids, including mass spectrometry-based lipidomics,
lipids are emerging as central players in cancer biology. Lipids function as essential …
lipids are emerging as central players in cancer biology. Lipids function as essential …
Fatty acid synthase: a metabolic oncogene in prostate cancer?
…, T Migita, D Tang, M Loda - Journal of cellular …, 2004 - Wiley Online Library
In 1920, Warburg suggested that tumors consistently rely on anaerobic pathways to convert
glucose to ATP even in the presence of abundant oxygen [Warberg, 1956] despite the fact …
glucose to ATP even in the presence of abundant oxygen [Warberg, 1956] despite the fact …
[PDF][PDF] Integrative clinical genomics of advanced prostate cancer
…, A Gopalan, J Gao, M Loda, RT Lis, M Bowden… - Cell, 2015 - cell.com
Toward development of a precision medicine framework for metastatic, castration-resistant
prostate cancer (mCRPC), we established a multi-institutional clinical sequencing …
prostate cancer (mCRPC), we established a multi-institutional clinical sequencing …
The landscape of somatic copy-number alteration across human cancers
A powerful way to discover key genes with causal roles in oncogenesis is to identify
genomic regions that undergo frequent alteration in human cancers. Here we present high-…
genomic regions that undergo frequent alteration in human cancers. Here we present high-…
[HTML][HTML] Targeting potential drivers of COVID-19: Neutrophil extracellular traps
… Massimo Loda … M. Egeblad reported "other" from Santhera during the conduct of the study;
and … Loda reviewed the autopsy pathology. BJ Barnes, JM Adrover, A. Baxter-Stoltzfus, A…
and … Loda reviewed the autopsy pathology. BJ Barnes, JM Adrover, A. Baxter-Stoltzfus, A…
[PDF][PDF] The molecular taxonomy of primary prostate cancer
…, SM Lippman, J Liu, W Liu, L Lochovsky, M Loda… - Cell, 2015 - cell.com
There is substantial heterogeneity among primary prostate cancers, evident in the spectrum
of molecular abnormalities and its variable clinical course. As part of The Cancer Genome …
of molecular abnormalities and its variable clinical course. As part of The Cancer Genome …
Neutrophil extracellular traps contribute to immunothrombosis in COVID-19 acute respiratory distress syndrome
…, A Baxter-Stoltzfus, AC Borczuk, M Loda… - Blood, The Journal …, 2020 - ashpublications.org
COVID-19 affects millions of patients worldwide, with clinical presentation ranging from
isolated thrombosis to acute respiratory distress syndrome (ARDS) requiring ventilator support. …
isolated thrombosis to acute respiratory distress syndrome (ARDS) requiring ventilator support. …
Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses
…, R Bueno, M Gillette, M Loda… - Proceedings of the …, 2001 - National Acad Sciences
We have generated a molecular taxonomy of lung carcinoma, the leading cause of cancer
death in the United States and worldwide. Using oligonucleotide microarrays, we analyzed …
death in the United States and worldwide. Using oligonucleotide microarrays, we analyzed …
Multiclass cancer diagnosis using tumor gene expression signatures
…, T Poggio, W Gerald, M Loda… - Proceedings of the …, 2001 - National Acad Sciences
… Given m classes and m trained classifiers, a new sample takes the class of the classifier
with the largest real valued output class = arg max i=1...m f i , where f i is the real valued output …
with the largest real valued output class = arg max i=1...m f i , where f i is the real valued output …