User profiles for M. Lourenco

Mychael Lourenco

- Verified email at bioqmed.ufrj.br - Cited by 3601

MJ Lourenço

- Verified email at fc.ul.pt - Cited by 2723

Marta Lourenço

- Verified email at igc.gulbenkian.pt - Cited by 685

[HTML][HTML] Soluble amyloid-β oligomers as synaptotoxins leading to cognitive impairment in Alzheimer's disease

ST Ferreira, MV Lourenco, MM Oliveira… - Frontiers in cellular …, 2015 - frontiersin.org
Alzheimer’s disease (AD) is the most common form of dementia in the elderly, and affects
millions of people worldwide. As the number of AD cases continues to increase in both …

[HTML][HTML] How does brain insulin resistance develop in Alzheimer's disease?

FG De Felice, MV Lourenco, ST Ferreira - Alzheimer's & Dementia, 2014 - Elsevier
Compelling preclinical and clinical evidence supports a pathophysiological connection
between Alzheimer's disease (AD) and diabetes. Altered metabolism, inflammation, and insulin …

Synaptopathies: synaptic dysfunction in neurological disorders–A review from students to students

K Lepeta, MV Lourenco, BC Schweitzer… - Journal of …, 2016 - Wiley Online Library
Synapses are essential components of neurons and allow information to travel coordinately
throughout the nervous system to adjust behavior to environmental stimuli and to control …

An efficient room-temperature silicon-based light-emitting diode

WL Ng, MA Lourenco, RM Gwilliam, S Ledain, G Shao… - Nature, 2001 - nature.com
There is an urgent requirement for an optical emitter that is compatible with standard, silicon-based
ultra-large-scale integration (ULSI) technology 1 . Bulk silicon has an indirect energy …

Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer's models

MV Lourenco, RL Frozza, GB de Freitas, H Zhang… - Nature medicine, 2019 - nature.com
Defective brain hormonal signaling has been associated with Alzheimer’s disease (AD), a
disorder characterized by synapse and memory failure. Irisin is an exercise-induced myokine …

[PDF][PDF] Evaluation of anti-tubercular activity of nicotinic and isoniazid analogues

MCS Lourenco, MVN de Souza, AC Pinheiro… - Arkivoc, 2007 - pdfs.semanticscholar.org
Several nicotinic and isoniazid derivatives, most of them containing nitro groups were
synthesized by our group, and evaluated for their in vitro antibacterial activity against …

[PDF][PDF] TNF-α mediates PKR-dependent memory impairment and brain IRS-1 inhibition induced by Alzheimer's β-amyloid oligomers in mice and monkeys

MV Lourenco, JR Clarke, RL Frozza, TR Bomfim… - Cell metabolism, 2013 - cell.com
Alzheimer's disease (AD) and type 2 diabetes appear to share similar pathogenic mechanisms.
dsRNA-dependent protein kinase (PKR) underlies peripheral insulin resistance in …

Medicinal plants with inhibitory properties against snake venoms

…, FK Ticli, S Marcussi, MV Lourenco… - Current Medicinal …, 2005 - ingentaconnect.com
Envenomations due to snake bites are commonly treated by parenteral administration of
horse or sheep-derived polyclonal antivenoms aimed at the neutralization of toxins. However, …

Thermal properties of ionic liquids and ionanofluids of imidazolium and pyrrolidinium liquids

CA Nieto de Castro, MJV Lourenço… - Journal of Chemical & …, 2010 - ACS Publications
… (21) reported measurements for [C 4 mpyrr][(CF 3 SO 2 ) 2 N] and [C 4 mim][CF 3 SO 3 ]
using the same instrument presented in this work with an estimated uncertainty of ± 0.005 W·m −…

Molten salts as engineering fluids–A review: Part I. Molten alkali nitrates

VMB Nunes, CS Queirós, MJV Lourenço, FJV Santos… - Applied energy, 2016 - Elsevier
Molten salts constitute an important class of fluids for high temperature applications, like
catalytic medium for coal gasification, molten salt oxidation of wastes or for latent or sensible …