[HTML][HTML] Soluble amyloid-β oligomers as synaptotoxins leading to cognitive impairment in Alzheimer's disease
Alzheimer’s disease (AD) is the most common form of dementia in the elderly, and affects
millions of people worldwide. As the number of AD cases continues to increase in both …
millions of people worldwide. As the number of AD cases continues to increase in both …
[HTML][HTML] How does brain insulin resistance develop in Alzheimer's disease?
Compelling preclinical and clinical evidence supports a pathophysiological connection
between Alzheimer's disease (AD) and diabetes. Altered metabolism, inflammation, and insulin …
between Alzheimer's disease (AD) and diabetes. Altered metabolism, inflammation, and insulin …
Synaptopathies: synaptic dysfunction in neurological disorders–A review from students to students
K Lepeta, MV Lourenco, BC Schweitzer… - Journal of …, 2016 - Wiley Online Library
Synapses are essential components of neurons and allow information to travel coordinately
throughout the nervous system to adjust behavior to environmental stimuli and to control …
throughout the nervous system to adjust behavior to environmental stimuli and to control …
An efficient room-temperature silicon-based light-emitting diode
WL Ng, MA Lourenco, RM Gwilliam, S Ledain, G Shao… - Nature, 2001 - nature.com
There is an urgent requirement for an optical emitter that is compatible with standard, silicon-based
ultra-large-scale integration (ULSI) technology 1 . Bulk silicon has an indirect energy …
ultra-large-scale integration (ULSI) technology 1 . Bulk silicon has an indirect energy …
Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer's models
Defective brain hormonal signaling has been associated with Alzheimer’s disease (AD), a
disorder characterized by synapse and memory failure. Irisin is an exercise-induced myokine …
disorder characterized by synapse and memory failure. Irisin is an exercise-induced myokine …
[PDF][PDF] Evaluation of anti-tubercular activity of nicotinic and isoniazid analogues
MCS Lourenco, MVN de Souza, AC Pinheiro… - Arkivoc, 2007 - pdfs.semanticscholar.org
Several nicotinic and isoniazid derivatives, most of them containing nitro groups were
synthesized by our group, and evaluated for their in vitro antibacterial activity against …
synthesized by our group, and evaluated for their in vitro antibacterial activity against …
[PDF][PDF] TNF-α mediates PKR-dependent memory impairment and brain IRS-1 inhibition induced by Alzheimer's β-amyloid oligomers in mice and monkeys
Alzheimer's disease (AD) and type 2 diabetes appear to share similar pathogenic mechanisms.
dsRNA-dependent protein kinase (PKR) underlies peripheral insulin resistance in …
dsRNA-dependent protein kinase (PKR) underlies peripheral insulin resistance in …
Medicinal plants with inhibitory properties against snake venoms
…, FK Ticli, S Marcussi, MV Lourenco… - Current Medicinal …, 2005 - ingentaconnect.com
Envenomations due to snake bites are commonly treated by parenteral administration of
horse or sheep-derived polyclonal antivenoms aimed at the neutralization of toxins. However, …
horse or sheep-derived polyclonal antivenoms aimed at the neutralization of toxins. However, …
Thermal properties of ionic liquids and ionanofluids of imidazolium and pyrrolidinium liquids
CA Nieto de Castro, MJV Lourenço… - Journal of Chemical & …, 2010 - ACS Publications
… (21) reported measurements for [C 4 mpyrr][(CF 3 SO 2 ) 2 N] and [C 4 mim][CF 3 SO 3 ]
using the same instrument presented in this work with an estimated uncertainty of ± 0.005 W·m −…
using the same instrument presented in this work with an estimated uncertainty of ± 0.005 W·m −…
Molten salts as engineering fluids–A review: Part I. Molten alkali nitrates
Molten salts constitute an important class of fluids for high temperature applications, like
catalytic medium for coal gasification, molten salt oxidation of wastes or for latent or sensible …
catalytic medium for coal gasification, molten salt oxidation of wastes or for latent or sensible …