Electrospray ionization for mass spectrometry of large biomolecules
JB Fenn, M Mann, CK Meng, SF Wong… - Science, 1989 - science.org
Electrospray ionization has recently emerged as a powerful technique for producing intact
ions in vacuo from large and complex species in solution. To an extent greater than has …
ions in vacuo from large and complex species in solution. To an extent greater than has …
The Perseus computational platform for comprehensive analysis of (prote) omics data
… & Mann, M. MaxQuant enables high peptide identification rates, individualized ppb-range
mass … & Mann, M. Protein interaction screening by quantitative immunoprecipitation combined …
mass … & Mann, M. Protein interaction screening by quantitative immunoprecipitation combined …
Mass spectrometry-based proteomics
R Aebersold, M Mann - Nature, 2003 - nature.com
… analyser that measures the mass-to-charge ratio (m/z) of the ionized analytes, and a detector
that registers the number of ions at each m/z value. Electrospray ionization (ESI) and matrix-…
that registers the number of ions at each m/z value. Electrospray ionization (ESI) and matrix-…
Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry
The recent abundance of genome sequence data has brought an urgent need for systematic
proteomics to decipher the encoded protein networks that dictate cellular function 1 . To …
proteomics to decipher the encoded protein networks that dictate cellular function 1 . To …
[HTML][HTML] FLICE, a novel FADD-homologous ICE/CED-3–like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex
To identify CAP3 and CAP4, components of the CD95 (Fas/APO-1) death-inducing signaling
complex, we utilized nano-electrospray tandem mass spectrometry, a recently developed …
complex, we utilized nano-electrospray tandem mass spectrometry, a recently developed …
Global-scale temperature patterns and climate forcing over the past six centuries
Spatially resolved global reconstructions of annual surface temperature patterns over the
past six centuries are based on the multivariate calibration of widely distributed high-resolution …
past six centuries are based on the multivariate calibration of widely distributed high-resolution …
Lysine acetylation targets protein complexes and co-regulates major cellular functions
Lysine acetylation is a reversible posttranslational modification of proteins and plays a key
role in regulating gene expression. Technological limitations have so far prevented a global …
role in regulating gene expression. Technological limitations have so far prevented a global …
Mass spectrometric sequencing of proteins from silver-stained polyacrylamide gels
… In the peptide map of band 5, we observed an intensive doubly charged peak at m/z 685.9
(Figure 5A). A series of ions assumed to be Y‘‘ ions, which specified the partial sequence EVS…
(Figure 5A). A series of ions assumed to be Y‘‘ ions, which specified the partial sequence EVS…
[HTML][HTML] Accurate proteome-wide label-free quantification by delayed normalization and maximal peptide ratio extraction, termed MaxLFQ
Protein quantification without isotopic labels has been a long-standing interest in the
proteomics field. However, accurate and robust proteome-wide quantification with label-free …
proteomics field. However, accurate and robust proteome-wide quantification with label-free …
Proteomic characterization of the human centrosome by protein correlation profiling
… The nanoLC MS/MS experiments were repeated with precursor ions selected from restricted
m/z ranges (m/z 350–550, 545–750 and 745–1,400) matched by pulsed extraction of the …
m/z ranges (m/z 350–550, 545–750 and 745–1,400) matched by pulsed extraction of the …