Superwarfarins were developed following the emergence of warfarin resistance in rodents.
Compared to warfarin, superwarfarins have much longer half‐lives and stronger affinity to …

In the many scientific endeavors that are driven by organic chemistry, unambiguous identification
of small molecules is of paramount importance. Over the past 50 years, NMR and other …

… m, corresponding to an effective detector distance of 2.2 m. All diffraction images were
acquired using a TVIPS TemCam-F416 CMOS camera and corrected to account for negative pixel …

Solving the atomic structure of metallic clusters is fundamental to understanding their optical,
electronic, and chemical properties. Herein we present the structure of the largest aqueous …

… a [M+H]+ peak at 1,141.3 Da (expected 1,140.5 Da), a [M+Na… –6.0 M urea, 0.5–4.5 M
guanidinium-HCl, 0.75 M HCl, 0.75 M … 8 or 10, or 0.75 M NaOH. Aggregate content was measured …

The relationship between sample thickness and quality of data obtained is investigated by
microcrystal electron diffraction (MicroED). Several electron microscopy (EM) grids containing …

… Crystals were formed by mixing a 1:1 ratio of protein solution and a precipitant solution
composed of 0.5 M NaNO 3 , 0.1 M CaCl 2 and 0.1 M MES–NaOH, pH 6.5, in a cold room at 4 C. …

… Crystals were formed by mixing a 1:1 ratio of protein solution and a precipitant solution
composed of 0.5 M NaNO 3 , 0.1 M CaCl 2 , 0.1 M MES–NaOH pH 6.5 in a cold room at 4 C. …

G protein–coupled receptors (GPCRs), or seven-transmembrane receptors, are a superfamily
of membrane proteins that are critically important to physiological processes in the human …

Microcrystal electron diffraction (MicroED) allows for macromolecular structure solution from
nanocrystals. To create crystals of suitable size for MicroED data collection, sample …