The poor oral bioavailability arising from poor aqueous solubility should make drug research
and development more difficult. Various approaches have been developed with a focus on …

Identifying both the commonalities and differences in brain structures among psychiatric
disorders is important for understanding the pathophysiology. Recently, the ENIGMA-…

After the initial discovery of activins as important regulators of reproduction, novel and diverse
roles have been unraveled for them. Activins are expressed in various tissues and have a …

Activin, myostatin and other members of the TGF-β superfamily signal through a combination
of type II and type I receptors, both of which are transmembrane serine/threonine kinases. …

A change in the glutamatergic system is thought to play an important role in the pathophysiology
of schizophrenia. The aim of this study was to investigate the changes in metabolites, …

… Author Nakataki recruited study participants and undertook additional statistical analysis.
Authors Sumitani, Taniguchi, Shibuya-Tayoshi, Numata, and Iga recruited study participants. …

Differential diagnosis is sometimes difficult in practical psychiatric settings, in terms of using
the current diagnostic system based on presenting symptoms and signs. The creation of a …

Vascular endothelial growth factor (VEGF) has been implicated in neuronal survival,
neuroprotection, regeneration, growth, differentiation, and axonal outgrowth, which are known to be …

The main purpose of the present study was to examine the relationship between quality of life
(QOL) and cognitive dysfunction in schizophrenia. Subjects were 61 stabilized outpatients. …

According to the operational diagnostic criteria, psychiatric disorders such as schizophrenia
(SZ), bipolar disorder (BD), major depressive disorder (MDD), and autism spectrum disorder …