Biochemical markers of alcoholism
…, MK Liisanantti, AET Nissinen, MJ Savolainen - 2007 - degruyter.com
… Hannuksela M, Kesäniemi YA, Savolainen MJ. Evaluation of plasma cholesteryl ester
transfer protein (CETP) activity as a marker of alcoholism. Alcohol Alcohol 1992; 27:557–62. …
transfer protein (CETP) activity as a marker of alcoholism. Alcohol Alcohol 1992; 27:557–62. …
Schizophrenia and sudden cardiac death—a review
…, M Savolainen, M Isohanni - Nordic journal of …, 2008 - Taylor & Francis
Schizophrenia is a devastating mental disorder, which is often associated with severe loss
of functioning and shortened life expectancy. Suicides and accidents are well-known causes …
of functioning and shortened life expectancy. Suicides and accidents are well-known causes …
[HTML][HTML] Safety, tolerability and sustained weight loss over 2 years with the once-daily human GLP-1 analog, liraglutide
…, A Rissanen, S Rössner, MJ Savolainen… - International journal of …, 2012 - nature.com
Objective: Having demonstrated short-term weight loss with liraglutide in this group of obese
adults, we now evaluate safety/tolerability (primary outcome) and long-term efficacy for …
adults, we now evaluate safety/tolerability (primary outcome) and long-term efficacy for …
[HTML][HTML] Salivary metabolomics for diagnosis and monitoring diseases: challenges and possibilities
E Hyvärinen, M Savolainen, JJW Mikkonen, AM Kullaa - Metabolites, 2021 - mdpi.com
Saliva is a useful biological fluid and a valuable source of biological information. Saliva contains
many of the same components that can be found in blood or serum, but the components …
many of the same components that can be found in blood or serum, but the components …
3 years of liraglutide versus placebo for type 2 diabetes risk reduction and weight management in individuals with prediabetes: a randomised, double-blind trial
…, M Savolainen, M Krempf, M Romon, M Laville… - The Lancet, 2017 - thelancet.com
… In this randomised, double-blind, placebo-controlled trial, adults with prediabetes and a
body-mass index of at least 30 kg/m 2 , or at least 27 kg/m 2 with comorbidities, were …
body-mass index of at least 30 kg/m 2 , or at least 27 kg/m 2 with comorbidities, were …
Genome-wide association study identifies multiple loci influencing human serum metabolite levels
Nuclear magnetic resonance assays allow for measurement of a wide range of metabolic
phenotypes. We report here the results of a GWAS on 8,330 Finnish individuals genotyped and …
phenotypes. We report here the results of a GWAS on 8,330 Finnish individuals genotyped and …
Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma
…, I Prokopenko, R Puls, A Ruokonen, MJ Savolainen… - Nature …, 2011 - nature.com
Concentrations of liver enzymes in plasma are widely used as indicators of liver disease.
We carried out a genome-wide association study in 61,089 individuals, identifying 42 loci …
We carried out a genome-wide association study in 61,089 individuals, identifying 42 loci …
[HTML][HTML] Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA
…, M Perola, S Blankenberg, MJ Savolainen… - Nature …, 2016 - nature.com
Genome-wide association studies have identified numerous loci linked with complex diseases,
for which the molecular mechanisms remain largely unclear. Comprehensive molecular …
for which the molecular mechanisms remain largely unclear. Comprehensive molecular …
High-throughput serum NMR metabonomics for cost-effective holistic studies on systemic metabolism
…, J Viikari, OT Raitakari, MJ Savolainen, M Ala-Korpela - Analyst, 2009 - pubs.rsc.org
A high-throughput proton (1H) nuclear magnetic resonance (NMR) metabonomics approach
is introduced to characterise systemic metabolic phenotypes. The methodology combines …
is introduced to characterise systemic metabolic phenotypes. The methodology combines …
Cholesteryl ester transfer protein TaqIB variant, high-density lipoprotein cholesterol levels, cardiovascular risk, and efficacy of pravastatin treatment: individual patient …
…, H Kauma, S Kakko, MJ Savolainen, M Arca… - Circulation, 2005 - Am Heart Assoc
Background— Several studies have reported that the cholesteryl ester transfer protein (CETP)
TaqIB gene polymorphism is associated with HDL cholesterol (HDL-C) levels and the risk …
TaqIB gene polymorphism is associated with HDL cholesterol (HDL-C) levels and the risk …