Cancer suppression is an important feature in the evolution of large and long-lived animals.
While some tumor suppression pathways are conserved among all multicellular organisms, …

Here we use a chromosome-level genome assembly of a prairie rattlesnake (Crotalus viridis),
together with Hi-C, RNA-seq, and whole-genome resequencing data, to study key features …

Cetaceans are a clade of highly specialized aquatic mammals that include the largest animals
that have ever lived. The largest whales can have ∼1,000× more cells than a human, with …

The tuatara (Sphenodon punctatus)—the only living member of the reptilian order
Rhynchocephalia (Sphenodontia), once widespread across Gondwana 1 , 2 —is an iconic species …

The risk of developing cancer should theoretically increase with both the number of cells
and the lifespan of an organism. However, gigantic animals do not get more cancer than …

Disease susceptibility and resistance are important factors for the conservation of endangered
species, including elephants. We analyzed pathology data from 26 zoos and report that …

Rapid technological improvements are democratizing access to high quality, chromosome-scale
genome assemblies. No longer the domain of only the most highly studied model …

Cancer is caused by genetic alterations that affect cellular fitness, and multicellular
organisms have evolved mechanisms to suppress cancer such as cell cycle checkpoints and …

Squamates include all lizards and snakes, and display some of the most diverse and
extreme morphological adaptations among vertebrates. However, compared with birds and …

Squamates include more than 11,000 extant species of lizards, snakes, and
amphisbaenians, and display a dazzling diversity of phenotypes across their over 200-million-year …