We describe Bioconductor infrastructure for representing and computing on annotated genomic
ranges and integrating genomic data with the statistical computing features of R and its …

Bioconductor is an open-source, open-development software project for the analysis and
comprehension of high-throughput data in genomics and molecular biology. The project aims …

Determining whether seed production is pollen limited has been an area of intensive
empirical study over the last two decades. Yet current evidence does not allow satisfactory …

Background Bacterial vaginosis (BV) is a common condition that is associated with numerous
adverse health outcomes and is characterized by poorly understood changes in the …

Recent technological advancements have enabled the profiling of a large number of genome-wide
features in individual cells. However, single-cell data present unique challenges that …

Recent studies have demonstrated that MyoD initiates a feed-forward regulation of skeletal
muscle gene expression, predicting that MyoD binds directly to many genes expressed …

ShortRead is a package for input, quality assessment, manipulation and output of high-throughput
sequencing data. ShortRead is provided in the R and Bioconductor environments, …

VariantAnnotation is an R / Bioconductor package for the exploration and annotation of genetic
variants. Capabilities exist for reading, writing and filtering variant call format (VCF) files. …

To the Editor: The microbiome has emerged as a key aspect of human biology and has been
implicated in many disease etiologies. Shotgun metagenomic sequencing is an approach …

Bacterial vaginosis (BV) is characterized by shifts in the vaginal microbiota from Lactobacillus
dominant to a microbiota with diverse anaerobic bacteria. Few studies have linked specific …