User profiles for N. Agier

nicolas agier

Sorbonne université
Verified email at upmc.fr
Cited by 3267

Total synthesis of a functional designer eukaryotic chromosome

…, A Yeluru, S Murugan, K Kandavelou, N Agier… - science, 2014 - science.org
Rapid advances in DNA synthesis techniques have made it possible to engineer viruses,
biochemical pathways and assemble bacterial genomes. Here, we report the synthesis of a …

[HTML][HTML] Epigenetic natural variation in Arabidopsis thaliana

…, N Dedhia, WR McCombie, N Agier… - PLoS …, 2007 - journals.plos.org
Cytosine methylation of repetitive sequences is widespread in plant genomes, occurring in
both symmetric (CpG and CpNpG) as well as asymmetric sequence contexts. We used the …

[HTML][HTML] Assessing the impact of transgenerational epigenetic variation on complex traits

…, V Saliba-Colombani, M Simon, N Agier… - PLoS …, 2009 - journals.plos.org
… , which demonstrates that DNA methylation differences can be stably inherited over at least
eight generations in the absence of extensive DNA sequence polymorphisms and with no

The use of metabolomics integrated with transcriptomic and proteomic studies for identifying key steps involved in the control of nitrogen metabolism in crops such as …

N Amiour, S Imbaud, G Clément, N Agier… - Journal of …, 2012 - academic.oup.com
… to long-term nitrogen (N)-deficient growth conditions at two important stages of plant
development have been studied. The impact of N deficiency was examined at the transcriptomic, …

[HTML][HTML] Telomere-to-telomere assemblies of 142 strains characterize the genome structural landscape in Saccharomyces cerevisiae

S O'donnell, JX Yue, OA Saada, N Agier, C Caradec… - Nature Genetics, 2023 - nature.com
… We found no substantial correlation between telomere length and ploidy, heterozygosity
or ecology (Extended Data Fig. 5b–d). We also examined telomere length variation between …

[HTML][HTML] Differentiation of Symbiotic Cells and Endosymbionts in Medicago truncatula Nodulation Are Coupled to Two Transcriptome-Switches

…, B Alunni, P Laporte, P Durand, N Agier… - PLoS …, 2010 - journals.plos.org
… The funders had no role in study design, data collection and analysis, decision to publish, or
… of the mutants TR3, TE7 and bacA showed no signs of differentiation by elongation and the …

DYRK1A interacts with the REST/NRSF-SWI/SNF chromatin remodelling complex to deregulate gene clusters involved in the neuronal phenotypic traits of Down …

…, Y Loe-Mie, K Benihoud, N Agier… - Human molecular …, 2009 - academic.oup.com
No axonal specific staining was performed in this study. However, taking into account that
neurons are polarized cells with multiple dendrites and a single axon, these results suggest …

Reconstruction of ancestral chromosome architecture and gene repertoire reveals principles of genome evolution in a model yeast genus

N Vakirlis, V Sarilar, G Drillon, A Fleiss, N Agier… - Genome …, 2016 - genome.cshlp.org
… We found no correlation between genome size and either the number of genes, the
cumulative size of coding sequences, or the transposable element content. However, we found a …

Characterizing meiotic chromosomes' structure and pairing using a designer sequence optimized for Hi‐C

H Muller, VF Scolari, N Agier, A Piazza… - Molecular systems …, 2018 - embopress.org
… Meiosis is the cell division where a diploid cell gives rise to four haploid gametes through
two rounds of chromosome segregation with no intervening replication. The prophase of the …

[PDF][PDF] Evidence for two main domestication trajectories in Saccharomyces cerevisiae linked to distinct bread-making processes

…, S Guezenec, A Bourgais, L Huyghe, N Agier… - Current Biology, 2021 - cell.com
… It can be the dominant species in sourdough, even in bakeries where no industrial starter is
used, suggesting that the species may colonize a sourdough from the bakery’s environment …