User profiles for N. Chiorazzi
 | Nicholas ChiorazziThe Feinstein Institute for Medical Research Verified email at Northwell.edu Cited by 33870 |
Chronic lymphocytic leukemia
N Chiorazzi, KR Rai, M Ferrarini - New England Journal of …, 2005 - Mass Medical Soc
Our concept of the pathogenesis of chronic lymphocytic leukemia has undergone remarkable
changes during the past decade. This review addresses the latest ideas concerning the …
changes during the past decade. This review addresses the latest ideas concerning the …
iwCLL guidelines for diagnosis, indications for treatment, response assessment, and supportive management of CLL
…, M Keating, E Montserrat, N Chiorazzi… - Blood, The Journal …, 2018 - ashpublications.org
The previous edition of the consensus guidelines of the International Workshop on Chronic
Lymphocytic Leukemia (iwCLL), published in 2008, has found broad acceptance by …
Lymphocytic Leukemia (iwCLL), published in 2008, has found broad acceptance by …
B cell chronic lymphocytic leukemia: lessons learned from studies of the B cell antigen receptor
N Chiorazzi, M Ferrarini - Annual review of immunology, 2003 - annualreviews.org
B cell chronic lymphocytic leukemia (B-CLL) is an accumulative disease of slowly proliferating
CD5 + B lymphocytes that develops in the aging population. Whereas some patients with …
CD5 + B lymphocytes that develops in the aging population. Whereas some patients with …
Ig V Gene Mutation Status and CD38 Expression As Novel Prognostic Indicators in Chronic Lymphocytic Leukemia: Presented in part at the 40th Annual Meeting of …
…, KR Rai, M Ferrarini, N Chiorazzi - Blood, The Journal …, 1999 - ashpublications.org
Cellular immunophenotypic studies were performed on a cohort of randomly selected IgM +
B-chronic lymphocytic leukemia (B-CLL) cases for which Ig V H and V L gene sequences …
B-chronic lymphocytic leukemia (B-CLL) cases for which Ig V H and V L gene sequences …
Relation of gene expression phenotype to immunoglobulin mutation genotype in B cell chronic lymphocytic leukemia
…, MR Grever, BD Cheson, N Chiorazzi… - The Journal of …, 2001 - rupress.org
… We profiled gene expression in CLL samples (n = 37) using Lymphochip cDNA microarrays
… in the majority of CLL samples than in DLBCL samples (n = 40). These genes fall into two …
… in the majority of CLL samples than in DLBCL samples (n = 40). These genes fall into two …
[HTML][HTML] In vivo measurements document the dynamic cellular kinetics of chronic lymphocytic leukemia B cells
…, KR Rai, MK Hellerstein, N Chiorazzi - The Journal of …, 2005 - Am Soc Clin Investig
Due to its relatively slow clinical progression, B cell chronic lymphocytic leukemia (B-CLL) is
classically described as a disease of accumulation rather than proliferation. However, …
classically described as a disease of accumulation rather than proliferation. However, …
Chronic lymphocytic leukemia B cells express restricted sets of mutated and unmutated antigen receptors.
…, M Ferrarini, N Chiorazzi - The Journal of …, 1998 - Am Soc Clin Investig
… 206) are from reference 39; the IgM CD5 B-CLL cells (n 63) are from this study. Statistically
significant differences (Fisher’s Exact test) were found in the 2% group between the CD5 and …
significant differences (Fisher’s Exact test) were found in the 2% group between the CD5 and …
The Bruton tyrosine kinase inhibitor PCI-32765 thwarts chronic lymphocytic leukemia cell survival and tissue homing in vitro and in vivo
…, MJ Keating, S O'Brien, N Chiorazzi… - Blood, The Journal …, 2012 - ashpublications.org
B-cell receptor (BCR) signaling is a critical pathway in the pathogenesis of several B-cell
malignancies, including chronic lymphocytic leukemia (CLL), and can be targeted by inhibitors …
malignancies, including chronic lymphocytic leukemia (CLL), and can be targeted by inhibitors …
Multiple distinct sets of stereotyped antigen receptors indicate a role for antigen in promoting chronic lymphocytic leukemia
…, D Messmer, KR Rai, M Ferrarini, N Chiorazzi - The Journal of …, 2004 - rupress.org
… B-CLL Ig H chain V sequences from our collection (n = 255) and the public databases (n =
197) were subjected to BLAST searches of both nucleotide and protein databases to identify …
197) were subjected to BLAST searches of both nucleotide and protein databases to identify …
Stereotyped B-cell receptors in one-third of chronic lymphocytic leukemia: a molecular classification with implications for targeted therapies
…, AW Langerak, DG Oscier, N Chiorazzi… - Blood, The Journal …, 2012 - ashpublications.org
Mounting evidence indicates that grouping of chronic lymphocytic leukemia (CLL) into
distinct subsets with stereotyped BCRs is functionally and prognostically relevant. However, …
distinct subsets with stereotyped BCRs is functionally and prognostically relevant. However, …