User profiles for N. Selem

Noha Selem

Master of Science in Biochemistry- German University in Cairo
Verified email at alumni2019.guc.edu.eg
Cited by 41

Mechanisms of action of docosahexaenoic acid in the nervous system

N Salem Jr, B Litman, HY Kim, K Gawrisch - Lipids, 2001 - Wiley Online Library
n-6 fats and away from n-3 fats due to the availability of linoleic-rich vegetable oils. Estimates
of the Paleolithic diet indicate a much greater intake of LCP and a ratio of n-3/n… intake of n-3 …

Dietary polyunsaturated fatty acids and depression: when cholesterol does not satisfy

JR Hibbeln, N Salem Jr - The American journal of clinical nutrition, 1995 - Elsevier
… and distribution of dietary n-6 and n-3 polyunsaturated essential … the last century suggest
that decreased n-3 fatty acid consumption … Long-chain n-3 polyunsaturate deficiency may also …

[HTML][HTML] Global survey of the omega-3 fatty acids, docosahexaenoic acid and eicosapentaenoic acid in the blood stream of healthy adults

…, MR Higgins, CA Weatherford, N Salem Jr - Progress in lipid …, 2016 - Elsevier
Studies reporting blood levels of the omega-3 polyunsaturated fatty acids, eicosapentaenoic
acid (EPA) and docosahexaenoic acid (DHA), were systematically identified in order to …

Increased dietary intake of ω-3-polyunsaturated fatty acids reduces pathological retinal angiogenesis

…, A Hellstrom, JX Kang, EY Chew, N Salem Jr… - Nature medicine, 2007 - nature.com
Many sight-threatening diseases have two critical phases, vessel loss followed by hypoxia-driven
destructive neovascularization. These diseases include retinopathy of prematurity and …

[HTML][HTML] Docosahexaenoic acid protects from dendritic pathology in an Alzheimer's disease mouse model

…, B Teter, O Ubeda, P Rostaing, A Triller, N Salem… - Neuron, 2004 - cell.com
… Here, we report that reduction of dietary n-3 PFA in an AD mouse model resulted in 80%–90%
losses of the p85α subunit of phosphatidylinositol 3-kinase and the postsynaptic actin-…

[HTML][HTML] Physiological compartmental analysis of α-linolenic acid metabolism in adult humans

RJ Pawlosky, JR Hibbeln, JA Novotny, N Salem - Journal of lipid research, 2001 - ASBMB
… -3 fatty acid intake for each subject could be estimated and for purposes of this analysis
upper and lower n-3 fatty acid limits were assigned. The mean predicted dietary intake values …

A diet enriched with the omega-3 fatty acid docosahexaenoic acid reduces amyloid burden in an aged Alzheimer mouse model

…, F Yang, B Teter, O Ubeda, N Salem… - Journal of …, 2005 - Soc Neuroscience
… Louis, MO) was the standard chow on which all animals were raised (n-6/n-3 ratio of 7:1);
(2) a DHA-depleting low n-3 PUFA test diet adequate in all other nutrients that we called “low-…

Let-7a/cMyc/CCAT1/miR-17–5p Circuit Re-sensitizes Atezolizumab Resistance in Triple Negative Breast Cancer through Modulating PD-L1

NA Selem, H Nafae, T Manie, RA Youness… - Pathology-Research and …, 2023 - Elsevier
… Upon stratification of BC patients, PD-L1 expression was observed to be higher in TNBC (n
= 12) than non-TNBC (n = 25) patients (P < 0.0001) (Fig. 1B). Moreover, PD-L1 was found to …

Arachidonic and docosahexaenoic acids are biosynthesized from their 18-carbon precursors in human infants.

N Salem Jr, B Wegher, P Mena… - Proceedings of the …, 1996 - National Acad Sciences
… amounts of n-3 fatty acid metabolites accumulated in plasma are greater than those of the
n-… 18:3n3 indicate that n-6 fatty acid conversion rates are greater than those of the n-3 family. …

A mutation in OTOF, encoding otoferlin, a FER-1-like protein, causes DFNB9, a nonsyndromic form of deafness

…, A El-Amraoui, M Mustapha, N Salem… - Nature …, 1999 - nature.com
… We found 4 putative N-glycosylation sites and 13 potential protein kinase C phosphorylation
sites. Sequence comparisons showed that otoferlin is homologous not only to the nematode …