Infection with Zika virus (ZIKV) is associated with human congenital fetal anomalies. To
model fetal outcomes in nonhuman primates, we administered Asian-lineage ZIKV …

Purpose To investigate the correspondence between arterial spin labeling (ASL) flow‐sensitive
alternating inversion recovery (FAIR) and ferumoxytol DCE MRI for the assessment of …

Non-contrast enhanced methods are needed to quantify placental perfusion to detect and
monitor pathophysiological changes during pregnancy. We evaluate the potential of an …

Histological analysis of the placenta plays an important role in the study of adverse pregnancy
outcomes. Placental lesions arising from infarctions, infection, and other insults are often …

Glutathione S-transferase omega 1 and omega 2 (GSTO1 and GSTO2) catalyze monomethyl
arsenate reduction, the rate-limiting reaction in arsenic biotransformation. As a step toward …

Purpose: Gemcitabine is a nucleoside analogue with activity against solid tumors. Gemcitabine
metabolic inactivation is catalyzed by cytidine deaminase (CDA) or, after phosphorylation…

We evaluate two ASL based techniques for non-contrast measurement of perfusion compared
with ferumoxytol-based DCE MRI in ten pregnant rhesus macaques. Localized regions of …

Purpose: The proteasome is a multisubunit cellular organelle that functions as a nonlysosomal
threonine protease. Proteasomes play a critical role in the degradation of proteins, …

Arsenic contaminates ground water worldwide. Methylation is an important reaction in the
biotransformation of arsenic. We set out to study the pharmacogenetics of human arsenic …

5, 10-Methylenetetrahydrofolate reductase (MTHFR) is an important enzyme in the folate
metabolic pathway. Common genetic polymorphisms in the human MTHFR gene are …