[HTML][HTML] AS03 adjuvanted AH1N1 vaccine associated with an abrupt increase in the incidence of childhood narcolepsy in Finland

…, C Hublin, I Julkunen, P Olsén, O Saarenpää-Heikkilä… - PloS one, 2012 - journals.plos.org
Background Narcolepsy is a chronic sleep disorder with strong genetic predisposition causing
excessive daytime sleepiness and cataplexy. A sudden increase in childhood narcolepsy …

Sleeping problems during pregnancy—a risk factor for postnatal depressiveness

…, P Pölkki, O Saarenpää-Heikkilä… - Archives of Women's …, 2019 - Springer
In the general population, sleeping problems can precede an episode of depression. We
hypothesized that sleeping problems during pregnancy, including insomnia symptoms, …

[HTML][HTML] Increased incidence and clinical picture of childhood narcolepsy following the 2009 H1N1 pandemic vaccination campaign in Finland

M Partinen, O Saarenpää-Heikkilä, I Ilveskoski… - PloS one, 2012 - journals.plos.org
Background Narcolepsy is a rare neurological sleep disorder especially in children who are
younger than 10 years. In the beginning of 2010, an exceptionally large number of Finnish …

Sleep habits and disorders in Finnish schoolchildren

OA SAARENPÄÄHEIKKILÄ… - Journal of Sleep …, 1995 - Wiley Online Library
A variety of epidemiological sleep parameters was evaluated in 574 Finnish schoolchildren (age
7 to 17 years) and in their parents (454 mothers and 390 fathers). Three questionnaire …

[HTML][HTML] No serological evidence of influenza A H1N1pdm09 virus infection as a contributing factor in childhood narcolepsy after Pandemrix vaccination campaign in …

…, M Sillanpää, SL Himanen, O Saarenpää-Heikkilä… - PloS one, 2013 - journals.plos.org
Background Narcolepsy cataplexy syndrome, characterised by excessive daytime sleepiness
and cataplexy, is strongly associated with a genetic marker, human leukocyte antigen (HLA…

[HTML][HTML] Trajectories of mothers' and fathers' depressive symptoms from pregnancy to 24 months postpartum

…, A Kylliäinen, P Pölkki, O Saarenpää-Heikkilä… - Journal of Affective …, 2020 - Elsevier
Objectives This study investigated trajectories of mothers’ and fathers’ depressive symptoms
from prenatal to 24 months postpartum. Prenatal correlates of the trajectories were also …

Maternal and paternal sleep during pregnancy in the Child-sleep birth cohort

EJ Paavonen, O Saarenpää-Heikkilä, P Pölkki… - Sleep medicine, 2017 - Elsevier
Study objectives Maternal and paternal sleep insufficiency during pregnancy appears to be
a risk factor for health and wellbeing in young families. Here, we evaluated the prevalence of …

Normal sleep development in infants: findings from two large birth cohorts

EJ Paavonen, O Saarenpää-Heikkilä, I Morales-Munoz… - Sleep Medicine, 2020 - Elsevier
Objective Sleep difficulties are highly prevalent and often persistent in young children, but
sometimes parents are worried about sleep symptoms that belong to the normative range …

[HTML][HTML] Antigenic differences between AS03 adjuvanted influenza A (H1N1) pandemic vaccines: implications for pandemrix-associated narcolepsy risk

…, T Kirjavainen, P Olsen, O Saarenpää-Heikkilä… - PloS one, 2014 - journals.plos.org
Background Narcolepsy results from immune-mediated destruction of hypocretin secreting
neurons in hypothalamus, however the triggers and disease mechanisms are poorly …

Maternal and paternal depressive symptoms and children's emotional problems at the age of 2 and 5 years: a longitudinal study

…, P Pölkki, O SaarenpääHeikkilä… - Journal of Child …, 2020 - Wiley Online Library
Background Maternal and paternal depressive symptoms are related to children's emotional
problems, but their combined effect remains unclear. Here, we constructed four parental …