Epithelial-mesenchymal transition (EMT) describes the molecular reprogramming and
phenotypic changes involved in the conversion of polarised immotile epithelial cells to motile …

This article is an updated report of a symposium held at the June 2000 annual meeting of
the American Society for Pharmacology and Experimental Therapeutics in Boston. The …

Epithelial to mesenchymal transition (EMT) facilitates tissue remodelling during embryonic
development and is viewed as an essential early step in tumour metastasis. We found that all …

For a tumour cell to metastasise it must successfully negotiate a number of events, requiring
a series of coordinated changes in the expression of many genes. MicroRNAs are small non-…

Circular RNAs (circRNAs), formed by non-sequential back-splicing of pre-mRNA transcripts,
are a widespread form of non-coding RNA in animal cells. However, it is unclear whether …

Epithelial to mesenchymal transition occurs during embryologic development to allow tissue
remodeling and is proposed to be a key step in the metastasis of epithelial-derived tumors. …

… Total RNA was isolated from cell lines, and real-time PCR was performed by using primers
as previously described (Gregory et al., 2008a). Primers for canine TGF-β isoforms and CFL2 …

Metastatic disease is a primary cause of cancer-related death, and factors governing tumor
cell metastasis have not been fully elucidated. Here, we address this question by using tumor …

… The breast cancer cell lines were characterized for miR-200 expression by Gregory et al. (…
The breast cancer cell lines were characterized for miR-200 expression by Gregory et al. (…

Epithelial tumor cells transit to a mesenchymal state in response to extracellular cues, in a
process known as epithelial-to-mesenchymal transition (EMT). The precise nature of these …