User profiles for P. Baillie-Johnson
Peter Baillie-JohnsonResearch Associate, University of Cambridge Verified email at cam.ac.uk Cited by 674 |
Organoids and the genetically encoded self‐assembly of embryonic stem cells
DA Turner, P Baillie‐Johnson, A Martinez Arias - BioEssays, 2016 - Wiley Online Library
Understanding the mechanisms of early embryonic patterning and the timely allocation of
specific cells to embryonic regions and fates as well as their development into tissues and …
specific cells to embryonic regions and fates as well as their development into tissues and …
Multi-axial self-organization properties of mouse embryonic stem cells into gastruloids
The emergence of multiple axes is an essential element in the establishment of the mammalian
body plan. This process takes place shortly after implantation of the embryo within the …
body plan. This process takes place shortly after implantation of the embryo within the …
Symmetry breaking, germ layer specification and axial organisation in aggregates of mouse embryonic stem cells
SC Van den Brink, P Baillie-Johnson, T Balayo… - …, 2014 - journals.biologists.com
… The aggregates needed to be in suspension for shape changes to occur (Baillie-Johnson et
… well, minimising the possibility of fusions (for details see Baillie-Johnson et al., 2014). The …
… well, minimising the possibility of fusions (for details see Baillie-Johnson et al., 2014). The …
Single-cell and spatial transcriptomics reveal somitogenesis in gastruloids
… Only embryonic cell types with at least one cluster comparison with a P value below 0.2
are shown. Using different P value thresholds to define upregulated genes does not have a …
are shown. Using different P value thresholds to define upregulated genes does not have a …
Anteroposterior polarity and elongation in the absence of extra-embryonic tissues and of spatially localised signalling in gastruloids: mammalian embryonic organoids
…, V Trivedi, P Baillie-Johnson… - …, 2017 - journals.biologists.com
The establishment of the anteroposterior (AP) axis is a crucial step during animal embryo
development. In mammals, genetic studies have shown that this process relies on signals …
development. In mammals, genetic studies have shown that this process relies on signals …
Wnt/β-catenin and FGF signalling direct the specification and maintenance of a neuromesodermal axial progenitor in ensembles of mouse embryonic stem cells
…, PC Hayward, P Baillie-Johnson, P Rué… - …, 2014 - journals.biologists.com
… Furthermore, using a recently developed 3D culture system of mESCs (Baillie-Johnson et
al., 2014; van den Brink et al., 2014), we show that a similar treatment of cell aggregates …
al., 2014; van den Brink et al., 2014), we show that a similar treatment of cell aggregates …
Generation of aggregates of mouse embryonic stem cells that show symmetry breaking, polarization and emergent collective behaviour in vitro
P Baillie-Johnson, SC Van den Brink, T Balayo… - JoVE (Journal of …, 2015 - jove.com
We have developed a protocol improving current Embryoid Body (EB) culture which allows
the study of self-organization, symmetry breaking, axial elongation and cell fate specification …
the study of self-organization, symmetry breaking, axial elongation and cell fate specification …
An epiblast stem cell-derived multipotent progenitor population for axial extension
S Edri, P Hayward, P Baillie-Johnson… - …, 2019 - journals.biologists.com
… somitic mesoderm upon transplantation (Baillie-Johnson et al., … along the anteroposterior
axis (Baillie-Johnson et al., 2018). … progenitors by fate mapping (Baillie-Johnson et al., 2018) …
axis (Baillie-Johnson et al., 2018). … progenitors by fate mapping (Baillie-Johnson et al., 2018) …
[PDF][PDF] Generating gastruloids from mouse embryonic stem cells
L Beccari, M Girgin, DA Turner, P Baillie-Johnson… - 2018 - repository.cam.ac.uk
Mouse embryonic stem cells (mESCs) can form all of the tissues of the developing embryo
in vivo; yet they develop into spatially disorganised structures when grown in vitro as …
in vivo; yet they develop into spatially disorganised structures when grown in vitro as …
Interactions between Nodal and Wnt signalling Drive Robust Symmetry-Breaking and Axial Organisation in Gastruloids (Embryonic Organoids)
…, L Alonso-Crisostomo, P Baillie-Johnson… - BioRxiv, 2016 - biorxiv.org
Generation of asymmetry within the early embryo is a critical step in the establishment of the
three body axes, providing a reference for the patterning of the organism. To study the …
three body axes, providing a reference for the patterning of the organism. To study the …