Towards comprehensive and quantitative proteomics for diagnosis and therapy of human disease
Towards comprehensive and quantitative proteomics for diagnosis and therapy of human
disease - Cifani - 2017 - PROTEOMICS - Wiley Online Library … Paolo Cifani … Paolo Cifani …
disease - Cifani - 2017 - PROTEOMICS - Wiley Online Library … Paolo Cifani … Paolo Cifani …
Rational targeting of a NuRD subcomplex guided by comprehensive in situ mutagenesis
… We found the interval from AA1872 to1883 to be highly significant (P = 2.93 × 10 −11 ) as
including outliers from the dataset. Using a sliding window to test all contiguous 12 AA …
including outliers from the dataset. Using a sliding window to test all contiguous 12 AA …
[PDF][PDF] A non-catalytic function of SETD1A regulates cyclin K and the DNA damage response
MLL/SET methyltransferases catalyze methylation of histone 3 lysine 4 and play critical roles
in development and cancer. We assessed MLL/SET proteins and found that SETD1A is …
in development and cancer. We assessed MLL/SET proteins and found that SETD1A is …
[PDF][PDF] A chemical strategy for protease substrate profiling
The dipeptidyl peptidases (DPPs) regulate hormones, cytokines, and neuropeptides by
cleaving dipeptides after proline from their amino termini. Due to technical challenges, many …
cleaving dipeptides after proline from their amino termini. Due to technical challenges, many …
MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia
In acute myeloid leukemia (AML), chemotherapy resistance remains prevalent and poorly
understood. Using functional proteomics of patient AML specimens, we identified MEF2C …
understood. Using functional proteomics of patient AML specimens, we identified MEF2C …
A comparison between the surface compression method and an interface reconstruction method for the VOF approach
P Cifani, WR Michalek, GJM Priems, JGM Kuerten… - Computers & …, 2016 - Elsevier
… We made use of the modified pressure p ^ = p − ρ g · x , with x the position vector. This
form allows an efficient numerical treatment of the steep density jump at the interface, on a …
form allows an efficient numerical treatment of the steep density jump at the interface, on a …
[HTML][HTML] Convergent organization of aberrant MYB complex controls oncogenic gene expression in acute myeloid leukemia
Dysregulated gene expression contributes to most prevalent features in human cancers.
Here, we show that most subtypes of acute myeloid leukemia (AML) depend on the aberrant …
Here, we show that most subtypes of acute myeloid leukemia (AML) depend on the aberrant …
[HTML][HTML] Targeting the CALR interactome in myeloproliferative neoplasms
… To control for potential differences in purification efficiencies due to differences in expression,
we normalized the LFQ of significantly impacted partners (P < 0.01) to the one of MBP (…
we normalized the LFQ of significantly impacted partners (P < 0.01) to the one of MBP (…
[HTML][HTML] An efficient geometric method for incompressible hydrodynamics on the sphere
We present an efficient and highly scalable geometric numerical method for two-dimensional
ideal fluid dynamics on the sphere. The starting point is Zeitlin's finite-dimensional model of …
ideal fluid dynamics on the sphere. The starting point is Zeitlin's finite-dimensional model of …
[HTML][HTML] RNA binding protein SYNCRIP maintains proteostasis and self-renewal of hematopoietic stem and progenitor cells
Tissue homeostasis is maintained after stress by engaging and activating the hematopoietic
stem and progenitor compartments in the blood. Hematopoietic stem cells (HSCs) are …
stem and progenitor compartments in the blood. Hematopoietic stem cells (HSCs) are …