User profiles for P. D'haeseleer

Patrik D'haeseleer

Lawrence Livermore National Laboratory
Verified email at llnl.gov
Cited by 10220

How does gene expression clustering work?

P D'haeseleer - Nature biotechnology, 2005 - nature.com
… Patrik D'haeseleer … Patrik D'haeseleerD'haeseleer, P. How does gene expression
clustering work?. Nat Biotechnol 23, 1499–1501 (2005). …

What are DNA sequence motifs?

P D'haeseleer - Nature biotechnology, 2006 - nature.com
Sequence motifs are becoming increasingly important in the analysis of gene regulation.
How do we define sequence motifs, and why should we use sequence logos instead of …

How does DNA sequence motif discovery work?

P D'haeseleer - Nature biotechnology, 2006 - nature.com
… Interestingly, the term 'Gibbs sampling' was borrowed by analogy from statistical mechanics
(via simulated annealing), where it refers to the inverse exponential relationship between …

[HTML][HTML] A phylogeny-driven genomic encyclopaedia of Bacteria and Archaea

…, A Lykidis, S Spring, IJ Anderson, P D'haeseleer… - Nature, 2009 - nature.com
Sequencing of bacterial and archaeal genomes has revolutionized our understanding of the
many roles played by microorganisms 1 . There are now nearly 1,000 completed bacterial …

Deep-sea oil plume enriches indigenous oil-degrading bacteria

…, R Chakraborty, EL Sonnenthal, P D'haeseleer… - Science, 2010 - science.org
The biological effects and expected fate of the vast amount of oil in the Gulf of Mexico from
the Deepwater Horizon blowout are unknown owing to the depth and magnitude of this event. …

Genetic network inference: from co-expression clustering to reverse engineering

P D'haeseleer, S Liang, R Somogyi - Bioinformatics, 2000 - academic.oup.com
P that all N rule tables are fully specified by n data points, and calculate how the number of
data points n needs to scale with P, the number of genes N, and connectivity K. For P ≈ 1 (ie …

An immunological approach to change detection: Algorithms, analysis and implications

P D'haeseleer, S Forrest… - Proceedings 1996 IEEE …, 1996 - ieeexplore.ieee.org
We present new results on a distributable change-detection method inspired by the natural
immune system. A weakness in the original algorithm was the exponential cost of generating …

Linear modeling of mRNA expression levels during CNS development and injury

P D'haeseleer, X Wen, S Fuhrman, R Somogyi - Biocomputing'99, 1999 - World Scientific
Large-scale gene expression data sets are revolutionizing the field of functional genomics.
However, few data analysis techniques fully exploit this entirely new class of data. We …

Microbial gene functions enriched in the Deepwater Horizon deep-sea oil plume

…, R Lamendella, JK Jansson, P D'haeseleer… - The ISME …, 2012 - academic.oup.com
… Genes encoding exopolyphosphatase (ppx) for inorganic polyphosphate degradation
and phytase for phytate degradation were detected with significantly (P<0.01 and P<0.05, …

The ModelSEED Biochemistry Database for the integration of metabolic annotations and the reconstruction, comparison and analysis of metabolic models for plants …

…, M DeJongh, JA Kimbrel, P D'haeseleer… - Nucleic acids …, 2021 - academic.oup.com
For over 10 years, ModelSEED has been a primary resource for the construction of draft
genome-scale metabolic models based on annotated microbial or plant genomes. Now being …