Most Indian groups descend from a mixture of two genetically divergent populations:
Ancestral North Indians (ANI) related to Central Asians, Middle Easterners, Caucasians, and …

RATIONALE To elucidate the extent to which the major cultural transformations of farming,
pastoralism, and shifts in the distribution of languages in Eurasia were accompanied by …

The study of human evolution has been revolutionized by inferences from ancient DNA
analyses. Key to these studies is the reliable estimation of the age of ancient specimens. High-…

We present the high-quality genome sequence of a ∼45,000-year-old modern human male
from Siberia. This individual derives from a population that lived before—or simultaneously …

Tourette's syndrome (TS) is a developmental disorder that has one of the highest familial
recurrence rates among neuropsychiatric diseases with complex inheritance. However, the …

Population mixture is an important process in biology. We present a suite of methods for
learning about population mixtures, implemented in a software package called ADMIXTOOLS, …

We present a high-quality genome sequence of a Neanderthal woman from Siberia. We
show that her parents were related at the level of half-siblings and that mating among close …

The textbook view that most germline mutations in mammals arise from replication errors is
indirectly supported by the fact that there are both more mutations and more cell divisions in …

The genetic structure of the indigenous hunter-gatherer peoples of southern Africa, the oldest
known lineage of modern human, is important for understanding human diversity. Studies …

Long-range migrations and the resulting admixtures between populations have been
important forces shaping human genetic diversity. Most existing methods for detecting and …