Objectives: The primary aim of this study was to explore the impact of falling for frail
community-dwelling older persons with and without cognitive impairments who have experienced a …

Depression is one of the most common non-motor symptoms of Parkinson's disease (PD) with
a large negative impact on the quality of life. Factors such as disease stage, subtype of PD …

Parkinson's disease (PD) is an important model for the role of dopamine in supporting
human cognition. However, despite the uniformity of midbrain dopamine depletion only some …

We examined the effect of bilateral subthalamic nucleus stimulation on levodopa-resistant
balance impairment in 14 patients with Parkinson's disease and 18 matched controls. …

Geriatrics focuses on a variety of multiorgan problems in a heterogeneous older population.
Therefore, most geriatric healthcare interventions are complex interventions. The UK …

OBJECTIVE: To assess whether a multifactorial fall prevention program was more effective
than usual geriatric care in preventing falls and reducing fear of falling in frail community-…

Background Parkinson's disease (PD) has been associated with set switching difficulty in
both the motor and the cognitive domain. However, the contribution of these set switching …

Objective Impulsivity is a “tendency to act prematurely without foresight.” Clinical experience
suggests that such impulsive behavior can impact on the fall risk in Parkinson’s disease (PD…

Parkinson's disease (PD) impairs the ability to shape postural responses to contextual
factors. It is unknown whether such inflexibility pertains to compensatory steps to overcome …

LRSAM1 mutations have been found in recessive and dominant forms of C harcot– M arie–
T ooth disease. Within one generation of the original D utch family in which the dominant …