User profiles for R. A. Standley
 | Robert StandleyPrincipal Scientist Clinical Research - Abbott Verified email at abbott.com Cited by 1050 |
Exercise and weight loss improve muscle mitochondrial respiration, lipid partitioning, and insulin sensitivity after gastric bypass surgery
Both Roux-en-Y gastric bypass (RYGB) surgery and exercise can improve insulin sensitivity
in individuals with severe obesity. However, the impact of RYGB with or without exercise on …
in individuals with severe obesity. However, the impact of RYGB with or without exercise on …
Physical activity unveils the relationship between mitochondrial energetics, muscle quality, and physical function in older adults
G Distefano, RA Standley, X Zhang… - Journal of Cachexia …, 2018 - Wiley Online Library
Background The concept of mitochondrial dysfunction in ageing muscle is highly controversial.
In addition, emerging evidence suggests that reduced muscle oxidative capacity and …
In addition, emerging evidence suggests that reduced muscle oxidative capacity and …
Chronological Age Does not Influence Ex-vivo Mitochondrial Respiration and Quality Control in Skeletal Muscle
Background: Considerable debate continues to surround the concept of mitochondrial
dysfunction in aging muscle. We tested the overall hypothesis that age per se does not influence …
dysfunction in aging muscle. We tested the overall hypothesis that age per se does not influence …
Skeletal muscle energetics and mitochondrial function are impaired following 10 days of bed rest in older adults
RA Standley, G Distefano, MB Trevino… - The Journals of …, 2020 - academic.oup.com
Background Older adults exposed to periods of inactivity during hospitalization, illness, or
injury lose muscle mass and strength. This, in turn, predisposes poor recovery of physical …
injury lose muscle mass and strength. This, in turn, predisposes poor recovery of physical …
Racial differences in peripheral insulin sensitivity and mitochondrial capacity in the absence of obesity
JP DeLany, JJ Dubé, RA Standley… - The Journal of …, 2014 - academic.oup.com
Context: African-American women (AAW) have an increased risk of developing type 2 diabetes
compared with Caucasian women (CW). Lower insulin sensitivity has been reported in …
compared with Caucasian women (CW). Lower insulin sensitivity has been reported in …
Prostaglandin and myokine involvement in the cyclooxygenase-inhibiting drug enhancement of skeletal muscle adaptations to resistance exercise in older adults
TA Trappe, RA Standley, B Jemiolo… - American Journal …, 2013 - journals.physiology.org
Twelve weeks of resistance training (3 days/wk) combined with daily consumption of the
cyclooxygenase-inhibiting drugs acetaminophen (4.0 g/day; n = 11, 64 ± 1 yr) or ibuprofen (1.2 g…
cyclooxygenase-inhibiting drugs acetaminophen (4.0 g/day; n = 11, 64 ± 1 yr) or ibuprofen (1.2 g…
Weight loss and exercise differentially affect insulin sensitivity, body composition, cardiorespiratory fitness, and muscle strength in older adults with obesity: a …
AM Brennan, RA Standley, SJ Anthony… - The Journals of …, 2022 - academic.oup.com
Background Aging-related disease risk is exacerbated by obesity and physical inactivity. It
is unclear how weight loss and increased activity improve risk in older adults. We aimed to …
is unclear how weight loss and increased activity improve risk in older adults. We aimed to …
Loss of mitochondrial energetics is associated with poor recovery of muscle function but not mass following disuse atrophy
MB Trevino, X Zhang, RA Standley… - American Journal …, 2019 - journals.physiology.org
Skeletal muscle atrophy is a clinically important outcome of disuse because of injury,
immobilization, or bed rest. Disuse atrophy is accompanied by mitochondrial dysfunction, which …
immobilization, or bed rest. Disuse atrophy is accompanied by mitochondrial dysfunction, which …
Dose response of exercise training following roux‐en‐Y gastric bypass surgery: a randomized trial
Objective Roux‐en‐Y gastric bypass (RYGB) surgery can cause profound weight loss and
improve overall cardiometabolic risk factors. Exercise (EX) training following RYGB can …
improve overall cardiometabolic risk factors. Exercise (EX) training following RYGB can …
Effects of β-hydroxy-β-methylbutyrate on skeletal muscle mitochondrial content and dynamics, and lipids after 10 days of bed rest in older adults
RA Standley, G Distefano, SL Pereira… - Journal of Applied …, 2017 - journals.physiology.org
Loss of muscle mass during periods of disuse likely has negative health consequences for
older adults. We have previously shown that β-hydroxy-β-methylbutyrate (HMB) …
older adults. We have previously shown that β-hydroxy-β-methylbutyrate (HMB) …