[PDF][PDF] Inducible FGFR-1 activation leads to irreversible prostate adenocarcinoma and an epithelial-to-mesenchymal transition
VD Acevedo, RD Gangula, KW Freeman, R Li, Y Zhang… - Cancer cell, 2007 - cell.com
Fibroblast Growth Factor Receptor-1 (FGFR1) is commonly overexpressed in advanced
prostate cancer (PCa). To investigate causality, we utilized an inducible FGFR1 (iFGFR1) …
prostate cancer (PCa). To investigate causality, we utilized an inducible FGFR1 (iFGFR1) …
[PDF][PDF] Homeostatic responses regulate selfish mitochondrial genome dynamics in C. elegans
Mutant mitochondrial genomes (mtDNA) can be viewed as selfish genetic elements that persist
in a state of heteroplasmy despite having potentially deleterious metabolic consequences…
in a state of heteroplasmy despite having potentially deleterious metabolic consequences…
Prostaglandin I2 Signaling and Inhibition of Group 2 Innate Lymphoid Cell Responses
…, MT Stier, V Polosuhkin, RD Gangula… - American journal of …, 2016 - atsjournals.org
Rationale: Group 2 innate lymphoid cells (ILC2s) robustly produce IL-5 and IL-13, cytokines
central to the asthma phenotype; however, the effect of prostaglandin (PG) I 2 on ILC2 …
central to the asthma phenotype; however, the effect of prostaglandin (PG) I 2 on ILC2 …
[HTML][HTML] Changes in subcutaneous white adipose tissue cellular composition and molecular programs underlie glucose intolerance in persons with HIV
SS Bailin, JA Kropski, RD Gangula, LT Hannah… - Frontiers in …, 2023 - frontiersin.org
Introduction Subcutaneous adipose tissue (SAT) is a critical regulator of systemic metabolic
homeostasis. Persons with HIV (PWH) have an increased risk of metabolic diseases and …
homeostasis. Persons with HIV (PWH) have an increased risk of metabolic diseases and …
Conditional activation of fibroblast growth factor receptor (FGFR) 1, but not FGFR2, in prostate cancer cells leads to increased osteopontin induction, extracellular …
KW Freeman, RD Gangula, BE Welm, M Ozen… - Cancer research, 2003 - AACR
Abstract Changes in the fibroblast growth factor receptor (FGFR) axis are often associated
with prostate cancer (CaP) progression. We have used chemically induced dimerization (CID) …
with prostate cancer (CaP) progression. We have used chemically induced dimerization (CID) …
Inducible prostate intraepithelial neoplasia with reversible hyperplasia in conditional FGFR1-expressing mice
KW Freeman, BE Welm, RD Gangula, JM Rosen… - Cancer research, 2003 - AACR
Accurate determination of the contributions of oncogenes toward tumor progression requires
their regulation. Herein, we created transgenic mice with prostate-specific expression of …
their regulation. Herein, we created transgenic mice with prostate-specific expression of …
Conditional activation of FGFR1 in the prostate epithelium induces angiogenesis with concomitant differential regulation of Ang-1 and Ang-2
SF Winter, VD Acevedo, RD Gangula, KW Freeman… - Oncogene, 2007 - nature.com
The expression of fibroblast growth factor receptor (FGFR)-1 correlates with angiogenesis
and is associated with prostate cancer (CaP) progression. To more precisely define the …
and is associated with prostate cancer (CaP) progression. To more precisely define the …
Versatile prostate cancer treatment with inducible caspase and interleukin-12
…, SA Desai, X Zhao, W Song, AZ Luo, RD Gangula… - Cancer research, 2005 - AACR
To establish optimized conditions for immunity against prostate cancer, we compared the
efficacy of multiple approaches in autochthonous and sc transgenic adenocarcinoma of the …
efficacy of multiple approaches in autochthonous and sc transgenic adenocarcinoma of the …
A Single-Cell Molecular Atlas of White Adipose Tissue Shows Differences in Myeloid and Lymphoid Cell Polarization in Type 2 Diabetes and HIV Infection
SS Bailin, JA Kropski, RD Gangula, LT Hannah… - bioRxiv, 2022 - biorxiv.org
Subcutaneous adipose tissue (SAT) is a critical regulator of systemic metabolic homeostasis.
Persons with HIV (PWH) have an increased risk of metabolic diseases and significant …
Persons with HIV (PWH) have an increased risk of metabolic diseases and significant …
White Adipose Tissue Compositional and Transcriptional Patterns with Progressive Glucose Intolerance in Persons with HIV
SS Bailin, JA Kropski, RD Gangula, L Hannah… - 2022 - europepmc.org
Subcutaneous adipose tissue (SAT) is a critical regulator of systemic metabolic homeostasis.
Persons with HIV (PWH) have an increased risk of metabolic diseases and significant …
Persons with HIV (PWH) have an increased risk of metabolic diseases and significant …