Background Global deaths from measles have decreased notably in past decades, due to
both increases in immunization rates and decreases in measles case fatality ratios (CFRs). …

Ebola is a highly lethal virus, which has caused at least 14 confirmed outbreaks in Africa
between 1976 and 2006. Using data from two epidemics [in Democratic Republic of Congo (…

Background Despite substantial improvement in the control of malaria and decreased
prevalence of malnutrition over the past two decades, both conditions remain heavy burdens that …

The objective of this research is to explore what would happen if the Hong Kong influenza
pandemic strain of 1968–1969 returned in 2000. We report the results of a series of …

Although vaccination has almost eliminated measles in parts of the world, the disease
remains a major killer in some high birth rate countries of the Sahel. On the basis of measles …

BackgroundThe first pandemic season of A/H3N2 influenza virus (1968/1969) resulted in
significant mortality in the United States, but it was the second pandemic season of A/H3N2 …

This paper shows the scale of global health research and the context in which we frame the
subsequent papers in the Series. In this Series paper, we provide a historical perspective on …

Background . The conflict in Darfur, Sudan, was responsible for the displacement of 1.8 million
civilians. We investigated a large outbreak of hepatitis E virus (HEV) infection in Mornay …

Measles epidemics in West Africa cause a significant proportion of vaccine-preventable
childhood mortality. Epidemics are strongly seasonal, but the drivers of these fluctuations are …

Background Each year, rotavirus gastroenteritis is responsible for about 37% of deaths from
diarrhea among children younger than 5 years of age worldwide, with a disproportionate …