Organic acids are valuable platform chemicals for future biorefining applications. Such
applications involve the conversion of low-cost renewable resources to platform sugars, which …

The sustainable production of biofuels will require the efficient utilization of lignocellulosic
biomass. A key barrier involves the creation of growth-inhibitory compounds by chemical …

There is current interest in finding sustainable remediation technologies for the removal of
contaminants from soil and groundwater. This review focuses on the combination of …

… coli MG1655 cell lines used in this study were obtained by the Gill lab from the Yale Coli
Genetic Stock Center and confirmed independently in the laboratory using phenotypic and PCR-…

A fundamental goal in biotechnology and biology is the development of approaches to
better understand the genetic basis of traits. Here we report a versatile method, trackable …

Methods for importing heterologous genes into genetically tractable hosts are among the most
desired tools of synthetic biology. Easy plug-and-play construction methods to rapidly test …

Global gene regulation throughout the Escherichia coli stress response to overexpression of
each of five recombinant proteins was evaluated. Reverse-transcriptase polymerase chain …

Research towards the commercialization of fungible biofuels has received a great deal of
recent interest and investment. To this end the microbial production of fatty acid-derived fuels …

… To that end, we present a route from ethyl 3-hydroxypropanoate (ethyl 3-HP, derived from …
as substrates with this chemistry could enable a more viable route to renewable ACN. …

Redox and energy balance plays a key role in determining microbial fitness. Efforts to redirect
bacterial metabolism often involve overexpression and deletion of genes surrounding key …