The canonical histone proteins are encoded by replication-dependent genes and must
rapidly reach high levels of expression during S phase. In metazoans the genes that encode …

… We thank Norman Zielke, Duronio laboratory members, and the anonymous reviewers for
corrections and helpful comments that improved the manuscript. This work was supported by …

Cells decide to proliferate or remain quiescent using signaling pathways that link information
about the cellular environment to the G 1 phase of the cell cycle. Progression through G 1 …

… E2f1 target genes in the endoreplicating embryonic midgut (Duronio and O’Farrell, 1995), and
… We thank David MacAlpine, members of the Fox and Duronio labs for helpful discussions, …

… Work on histone mRNA metabolism in the Marzluff and Duronio laboratories is supported
by NIH grants GM29832 and GM58921 (WFM) and National Science Foundation Career …

The conserved regulators of cell cycle progression--Cyclins, Cdc2 kinase, and String
phosphatase (Cdc25)--accommodate multiple modes of regulation during Drosophila …

Protein N-myristoylation refers to the covalent attachment of a myristoyl group (C14:0), via
amide linkage, to the NH2-terminal glycine residue of certain cellular and viral proteins. …

Overexpression of the E2F-1 cDNA in mammalian cells disrupts normal control of the cell
cycle and drives cells into S phase. Whereas eliminating E2F activity would test its inferred …

… Chemical Analysis of Fatty Acids Linked to r-myr Go,-To determine if r-myr Go, was … with
r-myr Go,. Significant amounts of myristate were detected in the acid hydrolysates prepared from r…

The E2F transcription factor is required for S phase in Drosophila. While it also triggers
expression of replication genes at the G1-S transition, the relevance of this transcription is not …