Biochemical signaling pathways in developmental processes have been extensively studied,
yet the role of mechanical cues during embryogenesis is much less explored. Here we …

… since, in virtually all cases, cells and nuclei in the embryo are convex, nearly spherical objects
whose volumes and surface areas are determined by the radius as V ∼ R 3 and A ∼ R 2 . …

The embryogenesis of the small nematode Caenorhabditis elegans is a remarkably robust
self-organization phenomenon. Cell migration trajectories in the early embryo, for example, …

… For simplicity we assumed the mother cell to be spherical (radius R 0 ), and we asked how
… R 0 + Δx and R 0 − Δx, yielding volumes V 1 = π/3·(R 0 + Δx)²·(2R 0 − Δx) and V 2 = π/3·(…

The unfolded protein response (UPR) allows cells to adjust the capacity of the endoplasmic
reticulum (ER) to the load of ER-associated tasks. We show that activation of the …

Organizing cell divisions in an embryo, especially coordinating cell cycles across larger
distances, is of crucial importance for the development of an animal. Here we show that cell-…

… by Nx and Vx, respectively, with indices x = c, r, ROI denoting the cytosol, the combination
of all … , ie, Fx = σNx (with x = {ROI,c,r}). Moreover, target membranes with index r and ROI …

… For simplicity we assumed the mother cell to be spherical (radius R 0 ), and we asked how
the volumetric ratio would be if the daughter cells emerged from a spindle that was displaced …

… Philipp Struntz, Rolf Fickentscher, Matthias Weiss. Experimental Physics 1, University of
Bayreuth, Bayreuth, Germany. Understanding dynamic processes in cells and multicellular …

… 2135-Pos Board B455 Robust Early Embryogenesis of Caenorhabditis Elegans due to
Mechanical Cues and Proper Cell Division Timing Rolf Fickentscher, Philipp Struntz, Matthias …