User profiles for R. Laaksonen
Reijo LaaksonenTampere University Verified email at tuni.fi Cited by 38599 |
Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants
…, M Fischer, T Kessler, C Willenborg, R Laaksonen… - Stroke, 2014 - Am Heart Assoc
Background and Purpose— Ischemic stroke (IS) and coronary artery disease (CAD) share
several risk factors and each has a substantial heritability. We conducted a genome-wide …
several risk factors and each has a substantial heritability. We conducted a genome-wide …
Phenotype standardization for statin‐induced myotoxicity
…, H Chinoy, RG Cooper, R Laaksonen… - Clinical …, 2014 - Wiley Online Library
Statins are widely used lipid‐lowering drugs that are effective in reducing cardiovascular
disease risk. Although they are generally well tolerated, they can cause muscle toxicity, which …
disease risk. Although they are generally well tolerated, they can cause muscle toxicity, which …
Low-density lipoprotein-independent effects of statins
J Davignon, R Laaksonen - Current opinion in lipidology, 1999 - journals.lww.com
Statins have pleiotropic properties that complement their cholesterol-lowering effects. These
properties may partly account for their established benefit in the prevention of coronary …
properties may partly account for their established benefit in the prevention of coronary …
Biological, clinical and population relevance of 95 loci for blood lipids
…, C Langenberg, LJ Launer, EG Lakatta, R Laaksonen… - Nature, 2010 - nature.com
Plasma concentrations of total cholesterol, low-density lipoprotein cholesterol, high-density
lipoprotein cholesterol and triglycerides are among the most important risk factors for …
lipoprotein cholesterol and triglycerides are among the most important risk factors for …
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease
We performed a meta-analysis of 14 genome-wide association studies of coronary artery
disease (CAD) comprising 22,233 individuals with CAD (cases) and 64,762 controls of …
disease (CAD) comprising 22,233 individuals with CAD (cases) and 64,762 controls of …
Large-scale association analysis identifies new risk loci for coronary artery disease
…, W Kratzer, K Kuulasmaa, M Laakso, R Laaksonen… - Nature …, 2013 - nature.com
Coronary artery disease (CAD) is the commonest cause of death. Here, we report an
association analysis in 63,746 CAD cases and 130,681 controls identifying 15 loci reaching …
association analysis in 63,746 CAD cases and 130,681 controls identifying 15 loci reaching …
Plasma ceramides predict cardiovascular death in patients with stable coronary artery disease and acute coronary syndromes beyond LDL-cholesterol
Aims The aim was to study the prognostic value of plasma ceramides (Cer) as cardiovascular
death (CV death) markers in three independent coronary artery disease (CAD) cohorts. …
death (CV death) markers in three independent coronary artery disease (CAD) cohorts. …
Risk of acute coronary events and serum concentration of asymmetrical dimethylarginine
Asymmetrical dimethylarginine (ADMA) is an endogenous nitric oxide synthase inhibitor, which
has been suggested to be a novel independent risk factor for endothelial dysfunction and …
has been suggested to be a novel independent risk factor for endothelial dysfunction and …
Quality of life 4 years after stroke.
ML Niemi, R Laaksonen, M Kotila, O Waltimo - Stroke, 1988 - Am Heart Assoc
… (55, R2 = 0.40; tendency to depression and difficulties in ambulation: R = 0.75, R2 = 0.57;
tendency to depression, difficulties in ambulation, and ADL: 1.0 RSQ R = 0.83, R2 = 0.69; …
tendency to depression, difficulties in ambulation, and ADL: 1.0 RSQ R = 0.83, R2 = 0.69; …
The profile of recovery from stroke and factors influencing outcome.
M Kotila, O Waltimo, ML Niemi, R Laaksonen… - Stroke, 1984 - Am Heart Assoc
… Waltimo O, Kaste M, Fogelholm R: Prognosis of patients with unilateral extracranial occlusion
… Zarith SH, Kahn R: Impairment and adaptation in chronic disabilities: spatial inattention. J …
… Zarith SH, Kahn R: Impairment and adaptation in chronic disabilities: spatial inattention. J …