[HTML][HTML] Substantial batch effects in TCGA exome sequences undermine pan-cancer analysis of germline variants
… For the six shared cancer types, we report an almost perfect correlation (r = 0.91) between
the average number of variants per sample calculated in our analysis to these numbers …
the average number of variants per sample calculated in our analysis to these numbers …
[HTML][HTML] Expanding cancer predisposition genes with ultra-rare cancer-exclusive human variations
It is estimated that up to 10% of cancer incidents are attributed to inherited genetic
alterations. Despite extensive research, there are still gaps in our understanding of genetic …
alterations. Despite extensive research, there are still gaps in our understanding of genetic …
Enhancing identification of cancer types via lowly-expressed microRNAs
The primary function of microRNAs (miRNAs) is to maintain cell homeostasis. In cancerous
tissues miRNAs’ expression undergo drastic alterations. In this study, we use miRNA …
tissues miRNAs’ expression undergo drastic alterations. In this study, we use miRNA …
Characteristics of myeloproliferative neoplasms in patients exposed to ionizing radiation following the Chernobyl nuclear accident
…, M Adam, E Fraenkel, R Rasnic… - American journal of …, 2019 - Wiley Online Library
Myeloproliferative neoplasms (MPNs) driver mutations are usually found in JAK2, MPL, and
CALR genes; however, 10%‐15% of cases are triple negative (TN). A previous study …
CALR genes; however, 10%‐15% of cases are triple negative (TN). A previous study …
[HTML][HTML] Genome wide screen of RNAi molecules against SARS-CoV-2 creates a broadly potent prophylaxis
…, A Naamti, I Falciatori, AC Berkyurek, R Rasnic… - bioRxiv, 2022 - ncbi.nlm.nih.gov
Expanding the arsenal of prophylactic approaches against SARS-CoV-2 is of utmost
importance, specifically those strategies that are resistant to antigenic drift in Spike. Here, we …
importance, specifically those strategies that are resistant to antigenic drift in Spike. Here, we …
[HTML][HTML] Chromoanagenesis landscape in 10,000 TCGA patients
R Rasnic, M Linial - Cancers, 2021 - mdpi.com
… identification (of samples from TCGA and the International Cancer Genome Consortium),
we observed that the chromoanagenesis rate is very similar for most cancer types, with R 2 of …
we observed that the chromoanagenesis rate is very similar for most cancer types, with R 2 of …
[HTML][HTML] From a genome-wide screen of RNAi molecules against SARS-CoV-2 to a validated broad-spectrum and potent prophylaxis
…, AC Berkyurek, R Rasnic, R Izuagbe… - Communications …, 2023 - nature.com
Expanding the arsenal of prophylactic approaches against SARS-CoV-2 is of utmost
importance, specifically those strategies that are resistant to antigenic drift in Spike. Here, we …
importance, specifically those strategies that are resistant to antigenic drift in Spike. Here, we …
Machine guarding, lockout/tagout, and the interlocked guard
R Rasnic, JA Capps - … Engineering Congress and …, 2004 - asmedigitalcollection.asme.org
Unguarded or poorly guarded machinery claims many limbs and lives each year. Similarly,
injuries from machinery undergoing maintenance and/or cleaning operations are far too …
injuries from machinery undergoing maintenance and/or cleaning operations are far too …
A scalable pipeline for SARS-CoV-2 replicon construction based on de-novo synthesis
AC Berkyurek, E Lee, O Weissbrod, R Rasnic… - bioRxiv, 2022 - biorxiv.org
Replicons are synthetic viral RNA molecules that recapitulate the self-replicating activities of
the virus but are missing its infectivity potential. Here, we report on a scalable pipeline to …
the virus but are missing its infectivity potential. Here, we report on a scalable pipeline to …
Reduced Mortality During Holidays and the COVID-19 Pandemic in Israel
Evidence suggests varied trends in mortality surrounding the holiday period. Most studies
support an association between increased mortality rates and holidays. We compare the effect …
support an association between increased mortality rates and holidays. We compare the effect …