Single-cell transcriptomic characterization of a gastrulating human embryo

RCV Tyser, E Mahammadov, S Nakanoh, L Vallier… - Nature, 2021 - nature.com
… as a representation of the typical expression pattern of a given mouse cluster, and then,
for each cell in the human gastrula, we used the “scmapCluster” function from the “scmap” R

A single-cell molecular map of mouse gastrulation and early organogenesis

…, FJ Calero-Nieto, C Mulas, X Ibarra-Soria, RCV Tyser… - Nature, 2019 - nature.com
… Batch effects were removed using the ‘fastMNN’ function in the scran R package on 50
principal components computed from the HVGs only. Correction was performed first between the …

Alien flora in grasslands adjacent to road and trail corridors in Glacier National Park, Montana (USA)

RW Tyser, CA Worley - Conservation Biology, 1992 - Wiley Online Library
… In the six road study sites a 100 m transect, designated as the “R” transect, was placed in the
center of the roadside area between the roadbed and the grassland border (Fig.2). Typically…

[HTML][HTML] Integration of spatial and single-cell transcriptomic data elucidates mouse organogenesis

…, ES Bardot, CHL Eng, RCV Tyser, R Argelaguet… - Nature …, 2022 - nature.com
Molecular profiling of single cells has advanced our knowledge of the molecular basis of
development. However, current approaches mostly rely on dissociating cells from tissues, …

[PDF][PDF] Spotted knapweed in natural area fescue grasslands: an ecological assessment

RW Tyser, CH Key - Northwest science., 1988 - rex.libraries.wsu.edu
… Sper.ies frequenr"r r-ategories rnere designated as follovs: common species (species occurring
in … Bet.i{een transect differences in number of points hitting disturbed soil r'rere compared …

Characterization of a common progenitor pool of the epicardium and myocardium

RCV Tyser, X Ibarra-Soria, K McDole, S Arcot Jayaram… - Science, 2021 - science.org
INTRODUCTION The vertebrate heart is composed of diverse cell types, all essential for
normal cardiac function. In the mouse, the earliest mesodermal progenitors of cardiomyocytes, …

[HTML][HTML] Recent advances in understanding cell types during human gastrulation

RCV Tyser, S Srinivas - Seminars in cell & developmental biology, 2022 - Elsevier
Gastrulation is a fundamental process during embryonic development, conserved across all
multicellular animals [1]. In the majority of metazoans, gastrulation is characterised by large …

Calcium handling precedes cardiac differentiation to initiate the first heartbeat

RCV Tyser, AMA Miranda, C Chen, SM Davidson… - Elife, 2016 - elifesciences.org
10.7554/eLife.17113.001 The mammalian heartbeat is thought to begin just prior to the
linear heart tube stage of development. How the initial contractions are established and the …

Defining murine organogenesis at single-cell resolution reveals a role for the leukotriene pathway in regulating blood progenitor formation

…, V Ladopoulos, A Scialdone, DJ Jörg, RCV Tyser… - Nature cell …, 2018 - nature.com
… We then ran the pairs classifier 15 implemented in the scran 34 R package to compare the
human foregut stem cell samples to the mouse endodermal cells from the foregut, midgut and …

[PDF][PDF] Effects of cholesterol depletion on compartmentalized cAMP responses in adult cardiac myocytes

SR Agarwal, DA MacDougall, R Tyser, SC Calaghan… - Biophysical …, 2011 - cell.com
We report the potential for photocontrol of cardiac excitation ranging from the cellular to the
tissue level using the photo-sensitive compound, azobenzene trimethyammonium bromide (…