Single-cell transcriptomic characterization of a gastrulating human embryo
RCV Tyser, E Mahammadov, S Nakanoh, L Vallier… - Nature, 2021 - nature.com
… as a representation of the typical expression pattern of a given mouse cluster, and then,
for each cell in the human gastrula, we used the “scmapCluster” function from the “scmap” R …
for each cell in the human gastrula, we used the “scmapCluster” function from the “scmap” R …
A single-cell molecular map of mouse gastrulation and early organogenesis
… Batch effects were removed using the ‘fastMNN’ function in the scran R package on 50
principal components computed from the HVGs only. Correction was performed first between the …
principal components computed from the HVGs only. Correction was performed first between the …
Alien flora in grasslands adjacent to road and trail corridors in Glacier National Park, Montana (USA)
RW Tyser, CA Worley - Conservation Biology, 1992 - Wiley Online Library
… In the six road study sites a 100 m transect, designated as the “R” transect, was placed in the
center of the roadside area between the roadbed and the grassland border (Fig.2). Typically…
center of the roadside area between the roadbed and the grassland border (Fig.2). Typically…
[HTML][HTML] Integration of spatial and single-cell transcriptomic data elucidates mouse organogenesis
Molecular profiling of single cells has advanced our knowledge of the molecular basis of
development. However, current approaches mostly rely on dissociating cells from tissues, …
development. However, current approaches mostly rely on dissociating cells from tissues, …
[PDF][PDF] Spotted knapweed in natural area fescue grasslands: an ecological assessment
RW Tyser, CH Key - Northwest science., 1988 - rex.libraries.wsu.edu
… Sper.ies frequenr"r r-ategories rnere designated as follovs: common species (species occurring
in … Bet.i{een transect differences in number of points hitting disturbed soil r'rere compared …
in … Bet.i{een transect differences in number of points hitting disturbed soil r'rere compared …
Characterization of a common progenitor pool of the epicardium and myocardium
RCV Tyser, X Ibarra-Soria, K McDole, S Arcot Jayaram… - Science, 2021 - science.org
INTRODUCTION The vertebrate heart is composed of diverse cell types, all essential for
normal cardiac function. In the mouse, the earliest mesodermal progenitors of cardiomyocytes, …
normal cardiac function. In the mouse, the earliest mesodermal progenitors of cardiomyocytes, …
[HTML][HTML] Recent advances in understanding cell types during human gastrulation
RCV Tyser, S Srinivas - Seminars in cell & developmental biology, 2022 - Elsevier
Gastrulation is a fundamental process during embryonic development, conserved across all
multicellular animals [1]. In the majority of metazoans, gastrulation is characterised by large …
multicellular animals [1]. In the majority of metazoans, gastrulation is characterised by large …
Calcium handling precedes cardiac differentiation to initiate the first heartbeat
RCV Tyser, AMA Miranda, C Chen, SM Davidson… - Elife, 2016 - elifesciences.org
10.7554/eLife.17113.001 The mammalian heartbeat is thought to begin just prior to the
linear heart tube stage of development. How the initial contractions are established and the …
linear heart tube stage of development. How the initial contractions are established and the …
Defining murine organogenesis at single-cell resolution reveals a role for the leukotriene pathway in regulating blood progenitor formation
… We then ran the pairs classifier 15 implemented in the scran 34 R package to compare the
human foregut stem cell samples to the mouse endodermal cells from the foregut, midgut and …
human foregut stem cell samples to the mouse endodermal cells from the foregut, midgut and …
[PDF][PDF] Effects of cholesterol depletion on compartmentalized cAMP responses in adult cardiac myocytes
SR Agarwal, DA MacDougall, R Tyser, SC Calaghan… - Biophysical …, 2011 - cell.com
We report the potential for photocontrol of cardiac excitation ranging from the cellular to the
tissue level using the photo-sensitive compound, azobenzene trimethyammonium bromide (…
tissue level using the photo-sensitive compound, azobenzene trimethyammonium bromide (…