Eukaryotic cells create internal order by using protein motors to transport molecules and
organelles along cytoskeletal tracks. Recent genomic and functional studies suggest that five …

The microtubule-based kinesin motors and actin-based myosin motors generate motions
associated with intracellular trafficking, cell division, and muscle contraction. Early studies …

… Zeng, and members from the Vale Laboratory for comments on this manuscript. This work
was supported by the HHMI’s Collaborative Innovation Awards, NIH (R01-GM56322 to MKR), …

Axoplasm from the squid giant axon contains a soluble protein translocator that induces
movement of microtubules on glass, latex beads on microtubules, and axoplasmic organelles on …

μManager is an open-source, cross-platform desktop application, to control a wide variety of
motorized microscopes, scientific cameras, stages, illuminators, and other microscope …

Kinesin is a processive motor that takes 8.3-nm center-of-mass steps along microtubules for
each adenosine triphosphate hydrolyzed. Whether kinesin moves by a “hand-over-hand” or …

Signals in many biological processes can be amplified by recruiting multiple copies of
regulatory proteins to a site of action. Harnessing this principle, we have developed a protein …

… Since 2005, several members of Ron Vale's laboratory at UCSF, with the assistance of
contributors worldwide, have been developing µManager: a free, open-source software package …

… We acknowledge R. Ahmed, A. Kamphorst, and membersof the Vale laboratory for comments
and discussions. RDVis an investigator of the Howard Hughes Medical Institute. DKS was …

In recent years the kinesin superfamily has become so large that several different naming
schemes have emerged, leading to confusion and miscommunication. Here, we set forth a …