User profiles for R. van Raaphorst

Renske van Raaphorst

University of Louvain
Verified email at uclouvain.be
Cited by 483

Computational tools for the synthetic design of biochemical pathways

…, R Van Raaphorst, E Takano, R Breitling - Nature Reviews …, 2012 - nature.com
As the field of synthetic biology is developing, the prospects for de novo design of biosynthetic
pathways are becoming more and more realistic. Hence, there is an increasing need for …

Features and outcomes of 899 patients with drug-induced liver injury: the DILIN prospective study

…, RJ Torrance, R Van Raaphorst - Gastroenterology, 2015 - Elsevier
… −5 mixed injury.16, 17 The R ratio applied to each case was calculated based on values at
the onset of injury. In this study, we also evaluated a modified R-ratio that was based on peak …

Relating gastric scintigraphy and symptoms to motility capsule transit and pressure findings in suspected gastroparesis

…, S James, R Torrance, R Van Raaphorst… - …, 2018 - Wiley Online Library
Background Wireless motility capsule ( WMC ) findings are incompletely defined in suspected
gastroparesis. We aimed to characterize regional WMC transit and contractility in relation …

Opioid use and potency are associated with clinical features, quality of life, and use of resources in patients with gastroparesis

…, S James, R Torrance, R Van Raaphorst… - Clinical …, 2019 - Elsevier
Background & Aims Many patients with gastroparesis are prescribed opioids for pain control,
but indications for opioid prescriptions and the relationship of opioid use to gastroparesis …

Chromosome segregation drives division site selection in Streptococcus pneumoniae

R van Raaphorst, M Kjos… - Proceedings of the …, 2017 - National Acad Sciences
… cells with fluorescently labeled vancomycin (Van-FL) to image sites of cell-wall synthesis (33)
and measured the angle of the areas in the cell enriched with Van-FL relative to the long …

[HTML][HTML] CcrZ is a pneumococcal spatiotemporal cell cycle regulator that interacts with FtsZ and controls DNA replication by modulating the activity of DnaA

…, X Liu, GA Stamsås, S Pelliciari, R van Raaphorst… - Nature …, 2021 - nature.com
Most bacteria replicate and segregate their DNA concomitantly while growing, before cell
division takes place. How bacteria synchronize these different cell cycle events to ensure …

[PDF][PDF] Modulation of prey size reveals adaptability and robustness in the cell cycle of an intracellular predator

YG Santin, T Lamot, R van Raaphorst, J Kaljević… - Current Biology, 2023 - cell.com
Despite a remarkable diversity of lifestyles, bacterial replication has only been investigated
in a few model species. In bacteria that do not rely on canonical binary division for …

[PDF][PDF] Chromosome choreography during the non-binary cell cycle of a predatory bacterium

…, TNV Saaki, SK Govers, O Remy, R van Raaphorst… - Current Biology, 2021 - cell.com
In bacteria, the dynamics of chromosome replication and segregation are tightly coordinated
with cell-cycle progression and largely rely on specific spatiotemporal arrangement of the …

BactMAP: An R package for integrating, analyzing and visualizing bacterial microscopy data

R van Raaphorst, M Kjos… - Molecular microbiology, 2020 - Wiley Online Library
High‐throughput analyses of single‐cell microscopy data are a critical tool within the field of
bacterial cell biology. Several programs have been developed to specifically segment …

[HTML][HTML] Synthetic genetic oscillators demonstrate the functional importance of phenotypic variation in pneumococcal-host interactions

AS Rueff, R Van Raaphorst, SD Aggarwal… - Nature …, 2023 - nature.com
… The fluorescence intensity was measured as the mean pixel intensity per cell using the R
immunofluorescence experiments were performed using R. The fluorescence intensity of each …