Stress (Takotsubo) cardiomyopathy—a novel pathophysiological hypothesis to explain catecholamine-induced acute myocardial stunning
…, S Prasad, PA Poole-Wilson, SE Harding - Nature clinical practice …, 2008 - nature.com
Stress cardiomyopathy, also referred to as Takotsubo cardiomyopathy, is an increasingly
recognized clinical syndrome characterized by acute reversible apical ventricular dysfunction. …
recognized clinical syndrome characterized by acute reversible apical ventricular dysfunction. …
Biomaterials in cardiac tissue engineering: ten years of research survey
QZ Chen, SE Harding, NN Ali, AR Lyon… - Materials Science and …, 2008 - Elsevier
Driven by enormous clinical need, myocardial tissue engineering has become a prime focus
of research within the field of tissue engineering. Myocardial tissue engineering combines …
of research within the field of tissue engineering. Myocardial tissue engineering combines …
[HTML][HTML] The intrinsic viscosity of biological macromolecules. Progress in measurement, interpretation and application to structure in dilute solution
SE Harding - Progress in biophysics and molecular biology, 1997 - Elsevier
… (4.3)), along with other useful hydrodynamic shape functions, are available using an
easy to use PC routine (ELLIPS2 (Harding et al., 1997b)) which not only covers the case of …
easy to use PC routine (ELLIPS2 (Harding et al., 1997b)) which not only covers the case of …
High Levels of Circulating Epinephrine Trigger Apical Cardiodepression in a β2-Adrenergic Receptor/Gi–Dependent Manner: A New Model of Takotsubo …
…, M Petrou, Z Zheng, J Gorelik, AR Lyon, SE Harding - Circulation, 2012 - Am Heart Assoc
Background— Takotsubo cardiomyopathy is an acute heart failure syndrome characterized
by myocardial hypocontractility from the mid left ventricle to the apex. It is precipitated by …
by myocardial hypocontractility from the mid left ventricle to the apex. It is precipitated by …
β2-Adrenergic Receptor Redistribution in Heart Failure Changes cAMP Compartmentation
The β 1 - and β 2 -adrenergic receptors (βARs) on the surface of cardiomyocytes mediate
distinct effects on cardiac function and the development of heart failure by regulating …
distinct effects on cardiac function and the development of heart failure by regulating …
Characterisation of a soft elastomer poly (glycerol sebacate) designed to match the mechanical properties of myocardial tissue
The myocardial tissue lacks significant intrinsic regenerative capability to replace the lost
cells. Therefore, the heart is a major target of research within the field of tissue engineering, …
cells. Therefore, the heart is a major target of research within the field of tissue engineering, …
Restoration of contractile function in isolated cardiomyocytes from failing human hearts by gene transfer of SERCA2a
F Del Monte, SE Harding, U Schmidt, T Matsui… - Circulation, 1999 - Am Heart Assoc
… 5 del Monte F, O’Gara P, Poole-Wilson PA, Yacoub M, Harding SE. Cell geometry and
contractile abnormalities of myocytes from failing human left ventricle. Cardiovasc Res.1995; 30:…
contractile abnormalities of myocytes from failing human left ventricle. Cardiovasc Res.1995; 30:…
Polylactide− poly (ethylene glycol) copolymers as drug delivery systems. 1. characterization of water dispersible micelle-forming systems
…, SE Dunn, MC Davies, L Illum, SS Davis, SE Harding… - Langmuir, 1996 - ACS Publications
Copolymers of polylactide and poly(ethylene glycol) (PLA−PEG), which self-disperse in
water to form spherical nonionic micelles, have been investigated as a novel biodegradable …
water to form spherical nonionic micelles, have been investigated as a novel biodegradable …
Nitric oxide attenuates cardiac myocyte contraction
…, TJ Williams, SE Harding - American Journal …, 1993 - journals.physiology.org
Cardiac muscle fibers have microvessels in close proximity, the distance from the nearest
capillary being no greater than 8 microns. We performed experiments on isolated, electrically …
capillary being no greater than 8 microns. We performed experiments on isolated, electrically …
Role of interleukin 6 in myocardial dysfunction of meningococcal septic shock
…, P O'Gara, S Nadel, DA Relman, SE Harding… - The Lancet, 2004 - thelancet.com
… SE Harding directed development of the myocyte contraction assay and planned and
analysed all experimental data relating to the myocyte contraction assay. M Levin developed the …
analysed all experimental data relating to the myocyte contraction assay. M Levin developed the …