Parkinson’s disease, the most common age-related movement disorder, is a progressive
neurodegenerative disease with unclear etiology. Key neuropathological hallmarks are Lewy …

Various post-translationally modified (PTM) proteoforms of alpha-synuclein (aSyn)—including
C-terminally truncated (CTT) and Serine 129 phosphorylated (Ser129-p) aSyn—…

Targeted cancer therapies block cancer growth and spread using small molecules. Many
molecular targets for an epidermal growth factor receptor (EGFR) selectively compete with the …

The variable configuration of Raman spectroscopic platforms is one of the major obstacles
in establishing Raman spectroscopy as a valuable physicochemical method within real-world …

Although channelrhodopsin (ChR) is a widely applied light-activated ion channel, important
properties such as light adaptation, photocurrent inactivation, and alteration of the ion …

Tyrosine kinase receptors are one of the main targets in cancer therapy. They play an essential
role in the modulation of growth factor signaling and thereby inducing cell proliferation …

Predictions about the cellular efficacy of drugs tested in vitro are usually based on the measured
responses of a few proteins or signal transduction pathways. However, cellular proteins …

The neuropathology of Alzheimer’s disease (AD) is characterized by hyperphosphorylated
tau neurofibrillary tangles (NFTs) and amyloid-beta (Aβ) plaques. Aβ plaques are …

Cervical cancer is the fourth most common cancer in women worldwide, and early detection
of its precancerous lesions can decrease mortality. Cytopathology, HPV testing, and …

… For example, El-Mashtoly et al. applied spontaneous Raman spectral imaging to visualize the
… El-Mashtoly is leading the Raman imaging group at the Department of Biophysics, PRODI, …