Lipid flippases are integral membrane proteins that use ATP hydrolysis to power the generation
of phospholipid asymmetry between the two leaflets of biological membranes, a process …

10.7554/eLife.29353.001 To optimize fitness a plant should monitor its metabolism to
appropriately control growth and defense. Primary metabolism can be measured by the universally …

Glucosinolates constitute the primary defense metabolites in Arabidopsis thaliana (Arabidopsis).
Indole and aliphatic glucosinolates, biosynthesized from tryptophan and methionine, …

In all eukaryotic cells, P4 ATPases, also named phospholipid flippases, generate phospholipid
asymmetry across biological membranes. This process is essential for cell survival, as it …

Casparian strip-generated apoplastic barriers not only control the radial flow of both water
and ions but may also constitute a hindrance for the rhizosecretion of stele-synthesized …

Within the cell, biosynthetic pathways are embedded in protein-protein interaction networks.
In Arabidopsis, the biosynthetic pathways of aliphatic and indole glucosinolate defense …

When investigating interactions between two proteins with complementary reporter tags in
yeast two-hybrid or split GFP assays, it remains troublesome to discriminate true- from false-…

To optimize fitness a plant should monitor its metabolism to appropriately control growth
and defense. Primary metabolism can be measured by the universally conserved TOR (Target …

Casparian strip-generated apoplastic barriers not only control the radial flow of both water
and ions but may also constitute a hindrance for the rhizosecretion of stele-synthesized …

Lipid flippases of the P4 ATPase family establish phospholipid asymmetry in eukaryotic cell
membranes and are involved in many essential cellular processes. The yeast …