User profiles for S. R. Piccolo
Stephen PiccoloBrigham Young University, Department of Biology Verified email at byu.edu Cited by 2872 |
Tools and techniques for computational reproducibility
SR Piccolo, MB Frampton - Gigascience, 2016 - academic.oup.com
When reporting research findings, scientists document the steps they followed so that others
can verify and build upon the research. When those steps have been described in sufficient …
can verify and build upon the research. When those steps have been described in sufficient …
The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions
…, G Ramsingh, CM Zwaan, S Noort, SR Piccolo… - Nature medicine, 2018 - nature.com
We present the molecular landscape of pediatric acute myeloid leukemia (AML) and
characterize nearly 1,000 participants in Children's Oncology Group (COG) AML trials. The COG–…
characterize nearly 1,000 participants in Children's Oncology Group (COG) AML trials. The COG–…
[HTML][HTML] A single-sample microarray normalization method to facilitate personalized-medicine workflows
Gene-expression microarrays allow researchers to characterize biological phenomena in a
high-throughput fashion but are subject to technological biases and inevitable variabilities …
high-throughput fashion but are subject to technological biases and inevitable variabilities …
Alternative preprocessing of RNA-Sequencing data in The Cancer Genome Atlas leads to improved analysis results
Motivation: The Cancer Genome Atlas (TCGA) RNA-Sequencing data are used widely for
research. TCGA provides ‘Level 3’ data, which have been processed using a pipeline specific …
research. TCGA provides ‘Level 3’ data, which have been processed using a pipeline specific …
Prediction of overall survival for patients with metastatic castration-resistant prostate cancer: development of a prognostic model through a crowdsourced challenge …
Background Improvements to prognostic models in metastatic castration-resistant prostate
cancer have the potential to augment clinical trial design and guide treatment strategies. In …
cancer have the potential to augment clinical trial design and guide treatment strategies. In …
[HTML][HTML] Combating subclonal evolution of resistant cancer phenotypes
Metastatic breast cancer remains challenging to treat, and most patients ultimately progress
on therapy. This acquired drug resistance is largely due to drug-refractory sub-populations (…
on therapy. This acquired drug resistance is largely due to drug-refractory sub-populations (…
Multiplatform single-sample estimates of transcriptional activation
SR Piccolo, MR Withers, OE Francis… - Proceedings of the …, 2013 - National Acad Sciences
Over the past two decades, many biotechnology platforms have been developed for high-throughput
gene expression profiling. However, because each platform is subject to technology…
gene expression profiling. However, because each platform is subject to technology…
Many bioinformatics programming tasks can be automated with ChatGPT
Computer programming is a fundamental tool for life scientists, allowing them to carry out
many essential research tasks. However, despite a variety of educational efforts, learning to …
many essential research tasks. However, despite a variety of educational efforts, learning to …
[HTML][HTML] A cloud-based workflow to quantify transcript-expression levels in public cancer compendia
PJ Tatlow, SR Piccolo - Scientific reports, 2016 - nature.com
Public compendia of sequencing data are now measured in petabytes. Accordingly, it is
infeasible for researchers to transfer these data to local computers. Recently, the National …
infeasible for researchers to transfer these data to local computers. Recently, the National …
Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease
…, S Peng, MA Peters, SR Piccolo… - Alzheimer's & …, 2016 - Wiley Online Library
Identifying accurate biomarkers of cognitive decline is essential for advancing early
diagnosis and prevention therapies in Alzheimer's disease. The Alzheimer's disease DREAM …
diagnosis and prevention therapies in Alzheimer's disease. The Alzheimer's disease DREAM …